Nanoengineered sprayable therapy for treating myocardial infarction

M Muñoz, C Eren Cimenci, K Goel, M Comtois-Bona… - ACS …, 2022 - ACS Publications
We report the development, as well as the in vitro and in vivo testing, of a sprayable
nanotherapeutic that uses surface engineered custom-designed multiarmed peptide grafted …

Bio‐conductive polymers for treating myocardial conductive defects: long‐term efficacy study

A Fu, Y Yang, J Wu, SH Li, Y Fan… - Advanced Healthcare …, 2022 - Wiley Online Library
Following myocardial infarction (MI), the resulting fibrotic scar is nonconductive and leads to
ventricular dysfunction via electrical uncoupling of the remaining viable cardiomyocytes. The …

Catheter–tissue contact optimizes pulsed electric field ablation with a large area focal catheter

SK Doshi, MC Flaherty, J Laughner… - Journal of …, 2024 - Wiley Online Library
Introduction Pulsed electric field (PEF) ablation relies on the intersection of a critical voltage
gradient with tissue to cause cell death. Field‐based lesion formation with PEF technologies …

Biophysics and electrophysiology of pulsed field ablation in normal and infarcted porcine cardiac ventricular tissue

D Miklavčič, A Verma, PRP Krahn, J Štublar, B Kos… - Scientific Reports, 2024 - nature.com
Abstract Pulsed Field Ablation (PFA) is a new ablation method being rapidly adopted for
treatment of atrial fibrillation, which shows advantages in safety and efficiency over …

[HTML][HTML] Endocardial infarct scar recognition by myocardial electrical impedance is not influenced by changes in cardiac activation sequence

G Amorós-Figueras, E Jorge, C Alonso-Martin… - Heart rhythm, 2018 - Elsevier
Background Measurement of myocardial electrical impedance can allow recognition of
infarct scar and is theoretically not influenced by changes in cardiac activation sequence …

Clinical utility of local impedance monitoring during pulmonary vein isolation

M Masuda, T Kanda, N Kurata, M Asai… - Journal of …, 2020 - Wiley Online Library
Introduction Local impedance (LI) at the tip of ablation catheter can be measured using a
recently available technology. We aimed to explore target LI measurements at each …

Electrophysiological and histological characterization of atrial scarring in a model of isolated atrial myocardial infarction

G Amorós-Figueras, S Casabella-Ramon… - Frontiers in …, 2023 - frontiersin.org
Background: Characterization of atrial myocardial infarction is hampered by the frequent
concurrence of ventricular infarction. Theoretically, atrial infarct scarring could be recognized …

Novel phenotype characterization utilizing electrical impedance myography signatures in murine spinal cord injury neurogenic bladder models

HHS Wang, H Thaker, A Bigger-Allen, JA Nagy… - Scientific Reports, 2023 - nature.com
Neurogenic bladder (NB) affects people of all ages. Electric impedance myography (EIM)
assesses localized muscle abnormalities. Here, we sought to investigate whether unique …

In vitro differentiation of human cardiac fibroblasts into myofibroblasts: characterization using electrical impedance

A Degache, FP de Gannes, A Garenne… - Biomedical Physics …, 2022 - iopscience.iop.org
Cardiac arrhythmias represent about 50% of the cardiovascular diseases which are the first
cause of mortality in the world. Implantable medical devices play a major role for treating …

Efficient identification of scars using heterogeneous model hierarchies

F Chegini, A Kopaničáková, R Krause, M Weiser - EP Europace, 2021 - academic.oup.com
Aims Detection and quantification of myocardial scars are helpful for diagnosis of heart
diseases and for personalized simulation models. Scar tissue is generally characterized by …