Simple and robust method for the synthesis of Metopimazine by utilising smile's rearrangement. Elimination of genotoxic impurities via derivatization

PKB Chalkappa, S Aralihalli, BM Praveen… - Journal of the Indian …, 2024 - Elsevier
A simple, efficient and scalable methodology has been developed for the synthesis of
Metopimazine, a dopamine D 2–receptor antagonist. Starting from nitrophenylthio …