Over the past decade, a number of new 1, 4-naphthoquinones have been isolated from
natural sources and new 1, 4-naphthoquinones with diverse structural features have been …

SUMMARY Mycothiol (MSH; AcCys-GlcN-Ins) is the major thiol found in Actinobacteria and
has many of the functions of glutathione, which is the dominant thiol in other bacteria and …

This paper reviews the antimicrobial research undertaken on South African medicinal plants
during the period 1997–2008. Antimicrobial methods (disc diffusion, minimum inhibitory …

Abstract The 1, 4-naphthoquinones (1, 4-NQs) are a diverse group of natural products found
in every kingdom of life. Plants, including many horticultural species, collectively synthesize …

There is an urgent need for the discovery and development of new antitubercular agents that
target new biochemical pathways and treat drug resistant forms of the disease. One …

ETHNOPHARMACOLOGICAL RELEVANCE: In South Africa, tuberculosis (TB) caused by
Mycobacterium tuberculosis is the most commonly notified disease and the fifth largest …

The ever-increasing incidence of drug-resistant Mycobacterium tuberculosis infections has
invigorated the focus on the discovery and development of novel treatment options. The …

The increasing drug resistance of M ycobacterium tuberculosis to the currently used drugs
and HIV coinfection has caused alarm in the international scientific community …

Over the past decades, a number of 1, 4‐naphthoquinones have been isolated from natural
resources and several of naphthoquinone derivatives with diverse structural motif have been …

Covering: 1994 to June 2008 Actinomycetes produce mycothiol as their major low molecular
weight thiol, which parallels the functions of glutathione found in prokaryotes and most Gram …