Inflammation is a major regulator of drug metabolizing enzymes and transporters: consequences for the personalization of drug treatment
F Stanke-Labesque, E Gautier-Veyret, S Chhun… - Pharmacology & …, 2020 - Elsevier
Inflammation is an evolutionary process that allows survival against acute infection or injury.
Inflammation is also a pathophysiological condition shared by numerous chronic diseases …
Inflammation is also a pathophysiological condition shared by numerous chronic diseases …
Ways to improve insights into clindamycin pharmacology and pharmacokinetics tailored to practice
L Armengol Alvarez, G Van de Sijpe, S Desmet… - Antibiotics, 2022 - mdpi.com
Given the increase in bacterial resistance and the decrease in the development of new
antibiotics, the appropriate use of old antimicrobials has become even more compulsory …
antibiotics, the appropriate use of old antimicrobials has become even more compulsory …
Pharmacokinetic interactions of antimalarial agents
PT Giao, PJ de Vries - Clinical pharmacokinetics, 2001 - Springer
Combination of antimalarial agents has been introduced as a response to widespread drug
resistance. The higher number of mutations required to express complete resistance against …
resistance. The higher number of mutations required to express complete resistance against …
Inflammation suppresses patients' ability to metabolize cytochrome P450 substrate drugs
CM White - Annals of Pharmacotherapy, 2022 - journals.sagepub.com
Objective: To assess the impact of inflammation on cytochrome P450 (CYP) drug
metabolism in human subjects. Data Sources: A PubMed search was done from 1980 to July …
metabolism in human subjects. Data Sources: A PubMed search was done from 1980 to July …
Current knowledge and challenges of antimalarial drugs for treatment and prevention in pregnancy
E Sevene, R González, C Menéndez - Expert opinion on …, 2010 - Taylor & Francis
Importance of the field: Malaria infection during pregnancy is a major public health problem
worldwide, with 50 million pregnancies exposed to the infection every year. Approximately …
worldwide, with 50 million pregnancies exposed to the infection every year. Approximately …
Pharmacokinetic interactions between ritonavir and quinine in healthy volunteers following concurrent administration
WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT• Malaria is widespread across some
areas of the world, most of which also bear the brunt of the human immunodeficiency virus …
areas of the world, most of which also bear the brunt of the human immunodeficiency virus …
Antimalarial agents
DA Casteel - Burger's medicinal chemistry and drug discovery, 2003 - Wiley Online Library
Malaria continues to be a major global health problem and seems to be increasing in some
parts of the world. By way of an introduction, relevant aspects of the disease, including …
parts of the world. By way of an introduction, relevant aspects of the disease, including …
Residual antimalarials in malaria patients from Tanzania–implications on drug efficacy assessment and spread of parasite resistance
EM Hodel, AM Kabanywanyi, A Malila, B Zanolari… - PLoS …, 2009 - journals.plos.org
Background Repeated antimalarial treatment for febrile episodes and self-treatment are
common in malaria-endemic areas. The intake of antimalarials prior to participating in an in …
common in malaria-endemic areas. The intake of antimalarials prior to participating in an in …
Effects of concurrent administration of nevirapine on the disposition of quinine in healthy volunteers
Objectives Nevirapine and quinine are likely to be administered concurrently in the
treatment of patients with HIV and malaria. Both drugs are metabolised to a significant extent …
treatment of patients with HIV and malaria. Both drugs are metabolised to a significant extent …
Flow‐through assay of quinine using solid contact potentiometric sensors based on molecularly imprinted polymers
AH Kamel, HEM Sayour - Electroanalysis: An International …, 2009 - Wiley Online Library
Miniaturized potentiometric membrane sensors for quinine incorporated with molecular
imprinted polymer (MIP) were synthesized and implemented. Planar PVC based polymeric …
imprinted polymer (MIP) were synthesized and implemented. Planar PVC based polymeric …