Ischemia–reperfusion–induced lung injury is characterized by nonspecific alveolar damage,
lung edema, and hypoxemia occurring within 72 hours after lung transplantation. The most …

Ex vivo preservation of transplanted organs is undergoing spectacular advances. Machine
perfusion is now used in common practice for abdominal and thoracic organ transportation …

We have previously demonstrated that a low-potassium dextran solution provides superior
and more reliable preservation of lungs for 12 hours than that provided by the commonly …

Background: Primary graft dysfunction (PGD) is a leading cause of early morbidity and
mortality in lung transplantation. We sought to identify risk factors for PGD using the United …

During the past 10 years, pulmonary transplantation has emerged as a successful mode of
surgical therapy for suitable patients with end-stage lung disease. Current preservation …

Although lung transplantation (LTx) has been established as a therapeutic approach for end-
stage respiratory failure, several problems remain to be solved. In addition to the serious …

The aim of this study was to assess the influence of preservation solution type and extra-or
intracellular composition on the occurrence of early graft dysfunction after clinical lung …

Abbreviations: ATP= adenosine triphosphate; ATPase= adenosine triphosphatase; cAMP=
cyclic adenosine monophosphate; cGMP= cyclic guanosine monophosphate; db-cAMP= a …

Background. If lungs could be retrieved for transplantation from non–heart-beating cadavers,
the shortage of donors might be significantly alleviated. Methods. Peak airway pressure …

Ischemia-reperfusion injury is one of the significant problems in clinical lung transplantation.
We investigated the effect of lung preservation with Euro-Collins solution (EC group) or low …