The intricate interplay between cellular senescence and alterations in the gut microbiome
emerges as a pivotal axis in the aging process, increasingly recognized for its contribution to …

Ferroptotic cancer therapy has been extensively investigated since the genesis of the
ferroptosis concept. However, the therapeutic efficacy of ferroptosis induction in …

Advancements in modern medicine have improved the quality of life across the globe and
increased the average lifespan of our population by multiple decades. Current estimates …

Simple Summary Iron is an essential element in human cells. Cells use iron for many
processes, such as proliferation, survival, DNA synthesis and energy production. However …

Accumulating evidence suggests that changes in the tumor microenvironment caused by
radiotherapy are closely related to the recurrence of glioma. However, the mechanisms by …

Diffuse large B-cell lymphoma (DLBCL), a heterogeneous lymphoid malignancy, poses a
significant threat to human health. The standard therapeutic regimen for patients with …

Therapy-induced senescent tumor cells have emerged as significant drivers of tumor
recurrence and disease relapse. Interestingly, reactive oxygen species (ROS) production …

Cellular senescence is a state of permanent proliferative arrest that occurs in response to
DNA damage-inducing endogenous and exogenous stresses, and is often accompanied by …

Aging encompasses a wide array of detrimental effects that compromise physiological
functions, elevate the risk of chronic diseases, and impair cognitive abilities. However, the …

The ELN gene encodes tropoelastin which is used to generate elastic fibers that insure
proper tissue elasticity. Decreased amounts of elastic fibers and/or accumulation of bioactive …