Microenvironment‐based diabetic foot ulcer nanomedicine

F Huang, X Lu, Y Yang, Y Yang, Y Li, L Kuai… - Advanced …, 2023 - Wiley Online Library
Diabetic foot ulcers (DFU), one of the most serious complications of diabetes, are essentially
chronic, nonhealing wounds caused by diabetic neuropathy, vascular disease, and bacterial …

Nanotechnology for targeted detection and removal of bacteria: opportunities and challenges

MJ Hajipour, AA Saei, ED Walker, B Conley… - Advanced …, 2021 - Wiley Online Library
The emergence of nanotechnology has created unprecedented hopes for addressing
several unmet industrial and clinical issues, including the growing threat so‐termed …

A focused review on hyaluronic acid contained nanofiber formulations for diabetic wound healing

ME Astaneh, N Fereydouni - International Journal of Biological …, 2023 - Elsevier
The significant clinical challenge presented by diabetic wounds is due to their impaired
healing process and increased risk of complications. It is estimated that a foot ulcer will …

Chondroitin sulfate-based composites: a tour d'horizon of their biomedical applications

MAS Abourehab, S Baisakhiya, A Aggarwal… - Journal of Materials …, 2022 - pubs.rsc.org
Chondroitin sulfate (CS), a natural anionic mucopolysaccharide, belonging to the
glycosaminoglycan family, acts as the primary element of the extracellular matrix (ECM) of …

A photo-triggering double cross-linked adhesive, antibacterial, and biocompatible hydrogel for wound healing

H Hu, X Zhai, W Li, S Ji, W Dong, W Chen, W Wei, Z Lu - Iscience, 2022 - cell.com
Full-thickness wounds, lacking the epidermis and entire dermis and extending into
subcutaneous fat, represent a common treatment challenge. Due to the loss of adnexal …

Chitosan based extruded nanofibrous bioscaffold for local delivery of mesenchymal stem cells to improve diabetic wound healing

A Abdollahi, HR Aghayan, Z Mousivand… - Stem Cell Research & …, 2024 - Springer
Abstract Background Mesenchymal stem cells (MSCs)-based treatment strategy has shown
promise in bolstering the healing process of chronic wounds in diabetic patients, who are at …

Engineered vasculogenic extracellular vesicles drive nonviral direct conversions of human dermal fibroblasts into induced endothelial cells and improve wound …

MA Rincon‐Benavides, NC Mendonca… - Advanced …, 2023 - Wiley Online Library
Vasculogenic cell therapies have emerged as a powerful tool to increase vascularization
and promote tissue repair/regeneration. Current approaches to cell therapies, however, rely …

A mechanistic perspective on the role of phytoconstituents-based pharmacotherapeutics and their topical formulations in chronic wound management

S Pattnaik, S Mohanty, SK Sahoo, C Mohanty - Journal of Drug Delivery …, 2023 - Elsevier
Prolonged inflammation and infection are the major factors that promote chronicity of the
wound. Despite the substantial advancements in therapeutic modalities, the treatment of …

A designed host defense peptide for the topical treatment of MRSA-infected diabetic wounds

A Vargas, G Garcia, K Rivara, K Woodburn… - International journal of …, 2023 - mdpi.com
Diabetes mellitus is a chronic disease characterized by metabolic dysregulation which is
frequently associated with diabetic foot ulcers that result from a severely compromised …

Sex-specific outcomes in cancer therapy: the central role of hormones

P Bakhshi, JQ Ho, S Zanganeh - Frontiers in Medical Technology, 2024 - frontiersin.org
Sex hormones play a pivotal role in modulating various physiological processes, with
emerging evidence underscoring their influence on cancer progression and treatment …