Schizophrenia (SZ) is a deleterious brain disorder affecting cognition, emotion and reality
perception. The most widely accepted neurochemical-hypothesis is the imbalance of …

Major depressive disorder (MDD) is a prevalent and serious mental disorder with high rates
of suicide and disability. However, the underlying pathogenesis of MDD is complicated and …

Schizophrenia (SZ) is a chronic psychiatric disorder affecting several people worldwide.
Mitochondrial DNA (mtDNA) variations could invoke changes in the OXPHOS system …

Terminalia chebula (TC), a kind of Combretaceae, is a widely used herb in India and East
Asia to treat cerebrovascular diseases. However, the potential mechanism of the …

We aimed to assess the effects of dexmedetomidine (DEX) on postoperative cognitive
function of sleep deprivation (SD) rats based on changes in inflammatory response. Male …

Background Tuberous sclerosis complex (TSC) is a rare monogenic disorder characterized
by benign tumors in multiple organs as well as a high prevalence of epilepsy, intellectual …

Abstract Background Fragile X syndrome (FXS) is a single-gene disorder that is the most
common heritable cause of intellectual disability and the most frequent monogenic cause of …

Pharmacological and genetic rodent models of schizophrenia play an important role in the
drug discovery pipeline, but quantifying the molecular similarity of such models with the …

The underlying mechanism of atypical antipsychotics in treating cognitive impairment in
schizophrenia is unclear. The aim of the present study was to evaluate the effects of …

Shuang-huang-lian Injection (SHLI) is the first successfully developed drug from traditional
Chinese medicine (TCM) powder for injection, since its use for the treatment of acute …