Effects of repeated 20-Hz electrical stimulation on functional recovery following peripheral nerve injury

S Park, C Liu, PJ Ward, PB Jaiswal… - … and neural repair, 2019 - journals.sagepub.com
One hour of 20-Hz continuous electrical stimulation (ES) applied at the time of injury
promotes the regeneration of axons in cut peripheral nerves. A more robust enhancement of …

Removal of the potassium chloride co-transporter from the somatodendritic membrane of axotomized motoneurons is independent of BDNF/TrkB signaling but is …

ET Akhter, RW Griffith, AW English, FJ Alvarez - eneuro, 2019 - eneuro.org
The potassium-chloride cotransporter (KCC2) maintains the low intracellular chloride found
in mature central neurons and controls the strength and direction of GABA/glycine synapses …

Regeneration of adult rat sensory and motor neuron axons through chimeric peroneal nerve grafts containing donor Schwann cells engineered to express different …

MJ Godinho, JL Staal, VS Krishnan, SI Hodgetts… - Experimental …, 2020 - Elsevier
Large peripheral nerve (PN) defects require bridging substrates to restore tissue continuity
and permit the regrowth of sensory and motor axons. We previously showed that cell-free …

Neuronal androgen receptor is required for activity dependent enhancement of peripheral nerve regeneration

PJ Ward, RA Davey, JD Zajac… - Developmental …, 2021 - Wiley Online Library
Neuronal activity after nerve injury can enhance axon regeneration and the restoration of
function. The mechanism for this enhancement relies in part on hormone receptors, and we …

Age-related loss of VGLUT1 excitatory, but not VGAT inhibitory, immunoreactive terminals on motor neurons in spinal cords of old sarcopenic male mice

VS Krishnan, T Shavlakadze, MD Grounds, SI Hodgetts… - Biogerontology, 2018 - Springer
Age-related changes in ventral lumbar spinal cord (L3–L5) were compared in young [3
month,(M)] and old (27 M) C57BL/6J male mice. The aged mice had previously been shown …

Role of the nervous system in sarcopenia: age related molecular and morphological changes in murine peripheral nerves and spinal cords, and analysis of the effects …

V Nambiar - 2017 - research-repository.uwa.edu.au
This PhD research studied the role of the peripheral and central nervous system, in the
context of the age related loss of skeletal muscle mass and function (sarcopenia). A time …