Toward defining deep brain stimulation targets in MNI space: a subcortical atlas based on multimodal MRI, histology and structural connectivity

S Ewert, P Plettig, N Li, MM Chakravarty, DL Collins… - Neuroimage, 2018 - Elsevier
Three-dimensional atlases of subcortical brain structures are valuable tools to reference
anatomy in neuroscience and neurology. For instance, they can be used to study the …

[HTML][HTML] Toward electrophysiology-based intelligent adaptive deep brain stimulation for movement disorders

WJ Neumann, RS Turner, B Blankertz, T Mitchell… - …, 2019 - Elsevier
Deep brain stimulation (DBS) represents one of the major clinical breakthroughs in the age
of translational neuroscience. In 1987, Benabid and colleagues demonstrated that high …

Integrative and network-specific connectivity of the basal ganglia and thalamus defined in individuals

DJ Greene, S Marek, EM Gordon, JS Siegel, C Gratton… - Neuron, 2020 - cell.com
The basal ganglia, thalamus, and cerebral cortex form an interconnected network implicated
in many neurological and psychiatric illnesses. A better understanding of cortico-subcortical …

Optimal deep brain stimulation sites and networks for cervical vs. generalized dystonia

A Horn, MM Reich, S Ewert, N Li… - Proceedings of the …, 2022 - National Acad Sciences
Dystonia is a debilitating disease with few treatment options. One effective option is deep
brain stimulation (DBS) to the internal pallidum. While cervical and generalized forms of …

A localized pallidal physiomarker in cervical dystonia

WJ Neumann, A Horn, S Ewert, J Huebl… - Annals of …, 2017 - Wiley Online Library
Objective Deep brain stimulation (DBS) allows for direct recordings of neuronal activity from
the human basal ganglia. In Parkinson's disease, a disease‐specific physiomarker was …

Deep brain stimulation for dystonia

M Vidailhet, MF Jutras, E Roze, D Grabli - Handbook of clinical neurology, 2013 - Elsevier
The few reported controlled studies show that bilateral stimulation of the globus pallidus
interna (GPi) is a safe and effective long-term treatment for hyperkinetic disorders. However …

Bilateral pallidal deep brain stimulation for the treatment of patients with dystonia-choreoathetosis cerebral palsy: a prospective pilot study

M Vidailhet, J Yelnik, C Lagrange, V Fraix… - The Lancet …, 2009 - thelancet.com
Background Cerebral palsy (CP) with dystonia-choreoathetosis is a common cause of
disability in children and in adults, and responds poorly to medical treatment. Bilateral …

Pallidal deep brain stimulation for monogenic dystonia: the effect of gene on outcome

S Tisch, KR Kumar - Frontiers in neurology, 2021 - frontiersin.org
Globus pallidus internus deep brain stimulation (GPi DBS) is the most effective intervention
for medically refractory segmental and generalized dystonia in both children and adults …

Probabilistic conversion of neurosurgical DBS electrode coordinates into MNI space

A Horn, AA Kühn, A Merkl, L Shih, R Alterman, M Fox - Neuroimage, 2017 - Elsevier
In neurosurgical literature, findings such as deep brain stimulation (DBS) electrode positions
are conventionally reported in relation to the anterior and posterior commissures of the …

Which patients with dystonia benefit from deep brain stimulation? A metaregression of individual patient outcomes

C Andrews, I Aviles-Olmos, M Hariz… - Journal of Neurology …, 2010 - jnnp.bmj.com
There is substantial variability in the responsiveness of dystonia patients to deep brain
stimulation (DBS), presumably due to the multiple causes of dystonia. This article presents …