The annotation of small molecules remains a major challenge in untargeted mass
spectrometry-based metabolomics. We here critically discuss structured elucidation …

Researchers worldwide are taking advantage of novel, commercially available,
technologies, such as ion mobility mass spectrometry (IM‐MS), for metabolomics and …

Ion mobility spectrometry is an analytical technique known for more than 100 years, which
entails separating ions in the gas phase based on their size, shape, and charge. While ion …

Aberrant sterol lipid metabolism is associated with physiological dysfunctions in the aging
brain and aging-dependent disorders such as neurodegenerative diseases. There is an …

Vitamin D, an important hormone with a central role in calcium and phosphate homeostasis,
is required for bone and muscle development as well as preservation of musculoskeletal …

Epilipids, a subset of the lipidome that comprises oxidized, nitrated, and halogenated lipid
species, show important biochemical activity in the regulation of redox lipid metabolism by …

Herein, we present the use of mass distribution-based isotopic shifts in high-resolution cyclic
ion mobility spectrometry–mass spectrometry (cIMS-MS)-based separations to characterize …

Omics studies such as metabolomics, lipidomics, and proteomics have become important for
understanding the mechanisms in living organisms. However, the compounds detected are …

Highlights•Ion mobility–mass spectrometry (IM–MS) supports the metabolomics and
lipidomics applications.•Collision cross-section (CCS) value is a valuable physiochemical …

Liquid chromatography/tandem mass spectrometry is firmly established today as the gold
standard technique for analysis of vitamin D, both for vitamin D status assessments as well …