Over the past decade, circular RNA (circRNA) research has evolved into a bona fide
research field shedding light on the functional consequence of this unique family of RNA …

Biomolecular condensates regulate transcription by dynamically compartmentalizing the
transcription machinery. Classic models of transcription regulation focus on the recruitment …

Fusion oncoproteins (FOs) arise from chromosomal translocations in~ 17% of cancers and
are often oncogenic drivers. Although some FOs can promote oncogenesis by undergoing …

The packaging of DNA into chromatin in eukaryotes regulates gene transcription, DNA
replication and DNA repair. ATP-dependent chromatin remodelling enzymes (re) arrange …

Fixing cells with paraformaldehyde (PFA) is an essential step in numerous biological
techniques as it is thought to preserve a snapshot of biomolecular transactions in living cells …

Biomolecular condensates organize cellular functions in the absence of membranes. These
membraneless organelles can form through liquid–liquid phase separation coalescing RNA …

Fusion oncoproteins (FOs) resulting from in-frame chromosomal translocations are
associated with many aggressive cancers with poor patient outcomes. Several FOs are now …

In eukaryotic cells, biological activities are executed in distinct cellular compartments or
organelles. Canonical organelles with membrane‐bound structures are well understood …

Prion-like domains (PLDs) are low-complexity protein sequences enriched within nucleic
acid-binding proteins including those involved in transcription and RNA processing. PLDs of …

Fusion transcription factors generated by genomic translocations are common drivers of
several types of cancers including sarcomas and leukemias. Oncofusions of the FET (FUS …