Reactive oxygen species: Physiological and physiopathological effects on synaptic plasticity: Supplementary issue: Brain plasticity and repair
TF Beckhauser, J Francis-Oliveira… - Journal of …, 2016 - journals.sagepub.com
In the mammalian central nervous system, reactive oxygen species (ROS) generation is
counterbalanced by antioxidant defenses. When large amounts of ROS accumulate …
counterbalanced by antioxidant defenses. When large amounts of ROS accumulate …
Inflammation and its role in neuroprotection, axonal regeneration and functional recovery after spinal cord injury
DJ Donnelly, PG Popovich - Experimental neurology, 2008 - Elsevier
Trauma to the central nervous system (CNS) triggers intraparenchymal inflammation and
activation of systemic immunity with the capacity to exacerbate neuropathology and …
activation of systemic immunity with the capacity to exacerbate neuropathology and …
Hydrogen sulfide and cellular redox homeostasis
Intracellular redox imbalance is mainly caused by overproduction of reactive oxygen species
(ROS) or weakness of the natural antioxidant defense system. It is involved in the …
(ROS) or weakness of the natural antioxidant defense system. It is involved in the …
Thematic Review Series: proteomics. An integrated omics analysis of eicosanoid biology1 [S]
MW Buczynski, DS Dumlao, EA Dennis - Journal of lipid research, 2009 - ASBMB
Eicosanoids have been implicated in a vast number of devastating inflammatory conditions,
including arthritis, atherosclerosis, pain, and cancer. Currently, over a hundred different …
including arthritis, atherosclerosis, pain, and cancer. Currently, over a hundred different …
Tocotrienols in health and disease: the other half of the natural vitamin E family
Tocochromanols encompass a group of compounds with vitamin E activity essential for
human nutrition. Structurally, natural vitamin E includes eight chemically distinct molecules …
human nutrition. Structurally, natural vitamin E includes eight chemically distinct molecules …
Cyclooxygenases, lipoxygenases, and epoxygenases in CNS: their role and involvement in neurological disorders
JW Phillis, LA Horrocks, AA Farooqui - Brain research reviews, 2006 - Elsevier
Three enzyme systems, cyclooxygenases that generate prostaglandins, lipoxygenases that
form hydroxy derivatives and leukotrienes, and epoxygenases that give rise to …
form hydroxy derivatives and leukotrienes, and epoxygenases that give rise to …
Fatty acid metabolism in the progression and resolution of CNS disorders
Recent advances in lipidomics and metabolomics have unveiled the complexity of fatty acid
metabolism and the fatty acid lipidome in health and disease. A growing body of evidence …
metabolism and the fatty acid lipidome in health and disease. A growing body of evidence …
Glycerophospholipids and glycerophospholipid-derived lipid mediators: a complex meshwork in Alzheimer's disease pathology
An increasing body of evidence suggested that intracellular lipid metabolism is dramatically
perturbed in various cardiovascular and neurodegenerative diseases with genetic and …
perturbed in various cardiovascular and neurodegenerative diseases with genetic and …
Loss of miR-29b following acute ischemic stroke contributes to neural cell death and infarct size
Glutathione depletion and 12-lipoxygenase-dependent metabolism of arachidonic acid are
known to be implicated in neurodegeneration associated with acute ischemic stroke. The …
known to be implicated in neurodegeneration associated with acute ischemic stroke. The …
Tocotrienols: the emerging face of natural vitamin E
Natural vitamin E includes eight chemically distinct molecules: α‐, β‐, γ‐, and δ‐tocopherols
and α‐, β‐, γ‐, and δ‐tocotrienols. More than 95% of all studies on vitamin E are directed …
and α‐, β‐, γ‐, and δ‐tocotrienols. More than 95% of all studies on vitamin E are directed …