Therapeutic potential of quercetin as a cardiovascular agent

RV Patel, BM Mistry, SK Shinde, R Syed… - European journal of …, 2018 - Elsevier
Flavonoids are integral components of various vegetation and in foods; consequently, they
represent an inevitable part of the diet. Historical and epidemiological proof recommend that …

[HTML][HTML] Discovery and resupply of pharmacologically active plant-derived natural products: A review

AG Atanasov, B Waltenberger… - Biotechnology …, 2015 - Elsevier
Medicinal plants have historically proven their value as a source of molecules with
therapeutic potential, and nowadays still represent an important pool for the identification of …

Navigating the chiral pool in the total synthesis of complex terpene natural products

ZG Brill, ML Condakes, CP Ting, TJ Maimone - Chemical reviews, 2017 - ACS Publications
The pool of abundant chiral terpene building blocks (ie,“chiral pool terpenes”) has long
served as a starting point for the chemical synthesis of complex natural products, including …

Organocatalytic cascade reactions as a new tool in total synthesis

C Grondal, M Jeanty, D Enders - Nature chemistry, 2010 - nature.com
The total synthesis of natural products and biologically active compounds, such as
pharmaceuticals and agrochemicals, has reached an extraordinary level of sophistication …

Continuous flow multi-step organic synthesis

D Webb, TF Jamison - Chemical Science, 2010 - pubs.rsc.org
Using continuous flow techniques for multi-step synthesis enables multiple reaction steps to
be combined into a single continuous operation. In this mini-review we discuss the current …

C H Activation: A Complementary Tool in the Total Synthesis of Complex Natural Products

DYK Chen, SW Youn - Chemistry–A European Journal, 2012 - Wiley Online Library
The recent advent of transition‐metal mediated C H activation is revolutionizing the
synthetic field and gradually infusing a “C H activation mind‐set” in both students and …

[HTML][HTML] Focus on the high therapeutic potentials of quercetin and its derivatives

A Septembre-Malaterre, A Boumendjel, ALS Seteyen… - Phytomedicine Plus, 2022 - Elsevier
Background Polyphenols and particularly flavonoids are of constant interest to the scientific
community. Flavonoids are investigated for their biological and pharmacological purposes …

Enantioselective Addition of Boronates to o-Quinone Methides Catalyzed by Chiral Biphenols

Y Luan, SE Schaus - Journal of the American Chemical Society, 2012 - ACS Publications
Chiral biphenols were found to catalyze the enantioselective asymmetric addition of aryl-or
alkenylboronates to o-quinone methides. Substituted 2-styryl phenols were obtained in good …

Applications of Knoevenagel condensation reaction in the total synthesis of natural products

MM Heravi, F Janati, V Zadsirjan - Monatshefte für Chemie-Chemical …, 2020 - Springer
The Knoevenagel condensation reaction is a prominent organic reaction commonly being
utilized in the total synthesis of natural and biologically potent products as a vital and …

Convergent strategies in total syntheses of complex terpenoids

D Urabe, T Asaba, M Inoue - Chemical Reviews, 2015 - ACS Publications
One of the largest classes of naturally occurring bioactive compounds, the terpenoids, is of
extraordinary pharmacological importance. 1, 2 The sphere of activity of terpenoids covers …