[HTML][HTML] Biomedical applications of selective metal complexes of indole, benzimidazole, benzothiazole and benzoxazole: A review (From 2015 to 2022)

AA Al Awadh - Saudi Pharmaceutical Journal, 2023 - Elsevier
Indole, benzoxazole benzothiazole and benzimidazole are excellent classes of organic
heterocyclic compounds. These compounds show significant application in pharmacy …

A review on the green synthesis of benzimidazole derivatives and their pharmacological activities

M Nardi, NCH Cano, S Simeonov, R Bence, A Kurutos… - Catalysts, 2023 - mdpi.com
Benzimidazoles and their derivatives play an extraordinarily significant role as therapeutic
agents, eg, antiulcer, analgesic, and anthelmintic drugs. The organic synthesis of …

Benzopyrone-mediated quinolones as potential multitargeting antibacterial agents

SR Li, CM Zeng, XM Peng, JP Chen, S Li… - European Journal of …, 2023 - Elsevier
A new type of benzopyrone-mediated quinolones (BMQs) was rationally designed and
efficiently synthesized as novel potential antibacterial molecules to overcome the global …

Two sandwich-type uranyl-containing polytungstates catalyze aerobic synthesis of benzimidazoles

YF Liu, QL Hu, XJ Chen, K Li, P Luo, GP Yang - Rare Metals, 2024 - Springer
Diversified synthetic strategies are extremely important for the structural diversity of uranium-
containing polyoxometalates (U-POMs) and their functional expansion. Herein, two …

Recent advances on biologically active coumarin-based hybrid compounds

M Yildirim, S Poyraz, M Ersatir - Medicinal Chemistry Research, 2023 - Springer
Coumarin hybrids have been designed and synthesized as an important new strategy in the
field of medicinal chemistry. Coumarin core has been shown to form various compounds to …

Design, synthesis and biological evaluation of novel coumarin derivatives as multifunctional ligands for the treatment of Alzheimer's disease

W Liu, L Wu, W Liu, L Tian, H Chen, Z Wu… - European Journal of …, 2022 - Elsevier
Multi-targeted directed ligands (MTDLs) are emerging as promising Alzheimer's disease
(AD) therapeutic possibilities. Coumarin is a multifunctional backbone with extensive …

The nano-based catalyst for the synthesis of benzimidazoles

RS Keri, V Adimule, P Kendrekar, BS Sasidhar - Topics in Catalysis, 2022 - Springer
The properties of benzimidazole and its derivatives have been studied over more than one
hundred years. The benzimidazole ring is an important pharmacophore in modern drug …

Synthetic and natural coumarins as potent anticonvulsant agents: A review with structure–activity relationship

RS Keri, S Budagumpi… - Journal of Clinical …, 2022 - Wiley Online Library
What is known and objective The main objective of this review is to highlight the most
relevant studies since 1990 (to date) in the area of medicinal chemistry aspects to provide a …

Synthesis, solvent-solute interactions (polar and non-polar), spectroscopic insights, topological aspects, Fukui functions, molecular docking, ADME, and donor …

AR Kumar, S Selvaraj, GPS Mol, M Selvaraj… - Journal of Molecular …, 2024 - Elsevier
The favorite heteroatom-containing compound, 2-(trifluoromethyl) benzimidazole (2TFMBI),
was synthesized and experimentally characterized using spectroscopic techniques. Density …

Benzimidazole hybrids as anticancer drugs: An updated review on anticancer properties, structure–activity relationship, and mechanisms of action (2019–2021)

LS Feng, WQ Su, JB Cheng, T Xiao, HZ Li… - Archiv der …, 2022 - Wiley Online Library
Cancer, characterized by a deregulation of the cell cycle which mainly results in a
progressive loss of cellular differentiation and uncontrolled cellular growth, remains a …