Objective To test the hypothesis that distinct subtypes of Alzheimer disease (AD) exist and
underlie the heterogeneity within AD, we conducted a systematic review and meta-analysis …

The broad importance of dementia is undisputed, with Alzheimer's disease justifiably getting
the most attention. However, dementia with Lewy bodies and Parkinson's disease dementia …

Since the classic papers of Kleist, Mayer Gross, and Critchley, constructional apraxia (CA)
has been considered to be a typical sign of a parietal lobe lesion, and as a precious tool to …

Although the diagnosis of dementia still is primarily based on clinical criteria, neuroimaging
is playing an increasingly important role. This is in large part due to advances in techniques …

Alzheimer's disease (AD) is a neurodegenerative disorder associated with cognitive decline.
Despite worldwide efforts to find a cure, no proper treatment has been developed yet, and …

Concomitant Alzheimer's disease (AD) pathology is a frequent event in the context of Lewy
body disease (LBD), occurring in approximately half of all cases. Evidence shows that LBD …

The PD-DLB psychosis complex found in Parkinson's disease (PD) and Dementia with Lewy
Bodies (DLB) includes hallucinations, Somatic Symptom/Functional Disorders, and …

Dementia with Lewy bodies (DLB) is neuropathologically defined by the presence of α-
synuclein aggregates, but many DLB cases show concurrent Alzheimer's disease pathology …

Oligodendrocytes are in contact with neurons, wrap axons with a myelin sheath that protects
their structural integrity, and facilitate nerve conduction. Oligodendrocytes also form a …

Almost all Alzheimer's disease (AD) therapeutic trials have failed in recent years. One of the
main reasons for failure is due to designing the disease-modifying clinical trials at the …