Over the past few years, considerable interest has been paid to the way in which social
expectations (hopes, hypes, fears) about new genomic technologies help shape, and in …

The new field of toxicogenomics presents a potentially powerful set of tools to better
understand the health effects of exposures to toxicants in the environment. At the request of …

Abstract Background and Objective Patient heterogeneity is the part of variability that can be
explained by certain patient characteristics (eg age, disease stage). Population …

Assessing the cost effectiveness of a new health intervention often requires modelling to
estimate the impact of the intervention on cost, survival and quality of life over the lifetime of …

Objective: In women with Human Epidermal growth Receptor 2 (HER2)-positive metastatic
breast cancer (MBC), Trastuzumab has become the standard of care but previous studies …

Aims: New sequencing technologies allow increased opportunities to use genomic-based
diagnostic tests (genomic tests) in routine clinical practice, which will impact healthcare …

Pharmacogenetics is an area of research encompassing a variety of different goals and
applications (for an overview see Nuffield Council on Bioethics1). Basic research interests …

Due to the significant boost in community expenditure with health topics, mainly regarding
drugs, numerous countries, have already put into operation, or are in the process of arguing …

The development of genomic tests has been rapid; however, the link between the
identification of gene-mutations and long-term patient health is still developing.[1, 2] As a …

Having multiple dimensions, uncertainties and several stakeholders, the costly
pharmacogenomics (PGx) is associated with dynamic implementation complexities …