Metabolomics is the study of the investigation of small molecules derived from cellular and
organism metabolism, which reflects the outcomes of the complex network of biochemical …

Personalized medicine is probably the most promising area being developed in modern
medicine. This approach attempts to optimize the therapies and the patient care based on …

The balance of programmed death-1 (PD-1)-expressing CD8+ T cells and regulatory T
(Treg) cells in the tumor microenvironment (TME) determines the clinical efficacy of PD-1 …

The pristine sample from the near-Earth carbonaceous asteroid (162173) Ryugu collected
by the Hayabusa2 spacecraft enabled us to analyze the pristine extraterrestrial material …

Background There is growing evidence that Alzheimer disease (AD) is a pervasive
metabolic disorder with dysregulation in multiple biochemical pathways underlying its …

We report primordial aqueous alteration signatures in water-soluble organic molecules from
the carbonaceous asteroid (162173) Ryugu by the Hayabusa2 spacecraft of JAXA. Newly …

In this review, we have attempted to highlight the advancements in the the field of 17 amino
acid determination using capillary electrophoresis. The technique has been developed 18 …

Immune checkpoint inhibitors (ICIs) have caused revolutionary changes in cancer treatment,
but low response rates remain a challenge. Semaphorin 4A (Sema4A) modulates the …

This review describes the analytical methods that have been developed over the years to
tackle the high polarity and non-chromophoric nature of amino acids (AAs). First, the …

A standardized data workflow is described for large-scale serum metabolomic studies using
multisegment injection-capillary electrophoresis-mass spectrometry. Multiplexed …