Toxicity of amphetamines: an update

M Carvalho, H Carmo, VM Costa, JP Capela… - Archives of …, 2012 - Springer
Amphetamines represent a class of psychotropic compounds, widely abused for their
stimulant, euphoric, anorectic, and, in some cases, emphathogenic, entactogenic, and …

Comprehensive review of cardiovascular toxicity of drugs and related agents

P Mladěnka, L Applová, J Patočka… - Medicinal research …, 2018 - Wiley Online Library
Cardiovascular diseases are a leading cause of morbidity and mortality in most developed
countries of the world. Pharmaceuticals, illicit drugs, and toxins can significantly contribute to …

[图书][B] Karch's pathology of drug abuse

SB Karch, O Drummer - 2008 - taylorfrancis.com
Written for practitioners in the field, this critically acclaimed bestseller provides authoritative
information focused on the investigation of drug-related deaths and practical approaches to …

Molecular and cellular mechanisms of ecstasy-induced neurotoxicity: an overview

JP Capela, H Carmo, F Remião, ML Bastos… - Molecular …, 2009 - Springer
Abstract “Ecstasy”[(±)-3, 4-methylenedioxymethamphetamine, MDMA, XTC, X, E] is a
psychoactive recreational hallucinogenic substance and a major worldwide drug of abuse …

The heart as a target for xenobiotic toxicity: the cardiac susceptibility to oxidative stress

VM Costa, F Carvalho, JA Duarte… - Chemical Research …, 2013 - ACS Publications
The heart is a target organ for oxidative stress-related injuries. Because of its very high
energetic metabolic demand, the heart has the highest rate of production of reactive oxygen …

Gold nanorod-sensitized cell death: microscopic observation of single living cells irradiated by pulsed near-infrared laser light in the presence of gold nanorods

H Takahashi, T Niidome, A Nariai, Y Niidome… - Chemistry …, 2006 - academic.oup.com
Pulsed near-infrared (near-IR) laser irradiation damaged cultured cells in the presence of
phosphatidylcholine-passivated gold nanorods (PC-NRs). When single cells were irradiated …

Neurotoxicity mechanisms of thioether ecstasy metabolites

JP Capela, C Macedo, PS Branco, LM Ferreira… - Neuroscience, 2007 - Elsevier
3, 4-Methylenedioxymethamphetamine (MDMA or “ecstasy”), is a widely abused,
psychoactive recreational drug that is known to induce neurotoxic effects. Human and rat …

Oxidative stress and drugs of abuse: an update

T Cunha-Oliveira, A Cristina Rego… - Mini-Reviews in …, 2013 - ingentaconnect.com
Drug addiction is a public health and social burden. Presently, the most abused illicit
substance is cannabis, followed by amphetamines, cocaine and opioids, with different …

Oxidation process of adrenaline in freshly isolated rat cardiomyocytes: formation of adrenochrome, quinoproteins, and GSH adduct

VM Costa, R Silva, LM Ferreira, PS Branco… - Chemical research in …, 2007 - ACS Publications
High concentrations of circulating biogenic catecholamines often exist during the course of
several cardiovascular disorders. Additionally, coronary dysfunctions are prominent and …

Combination effects of amphetamines under hyperthermia‐the role played by oxidative stress

DD Da Silva, E Silva, H Carmo - Journal of Applied Toxicology, 2014 - Wiley Online Library
Rise in body temperature is a life‐threatening consequence of 3, 4‐
methylenedioxymethamphetamine (MDMA, ecstasy) abuse. We evaluated the impact of …