[HTML][HTML] Non-coding RNAs: the riddle of the transcriptome and their perspectives in cancer

MA Diamantopoulos, P Tsiakanikas… - Annals of translational …, 2018 - ncbi.nlm.nih.gov
Non-coding RNAs (ncRNAs) constitute a heterogeneous group of RNA molecules in terms
of biogenesis, biological function as well as length and structure. These biological …

MicroRNAs: Tiny regulators of gene expression with pivotal roles in normal B-Cell development and B-Cell chronic lymphocytic leukemia

K Katsaraki, P Karousi, PI Artemaki, A Scorilas… - Cancers, 2021 - mdpi.com
Simple Summary The involvement of miRNAs in physiological cellular processes has been
well documented. The development of B cells, which is dictated by a miRNA-transcription …

[HTML][HTML] Downregulation of circ_0132266 in chronic lymphocytic leukemia promoted cell viability through miR-337-3p/PML axis

W Wu, Z Wu, Y Xia, S Qin, Y Li, J Wu, J Liang… - Aging (Albany …, 2019 - ncbi.nlm.nih.gov
Circular RNAs (circRNAs) have recently been reported to play crucial roles in various
regulatory processes and involved in cancer onset and progression. However, the potential …

A novel, mitochondrial, internal tRNA-derived RNA fragment possesses clinical utility as a molecular prognostic biomarker in chronic lymphocytic leukemia

P Karousi, PG Adamopoulos, SG Papageorgiou… - Clinical …, 2020 - Elsevier
Objectives Chronic lymphocytic leukemia (CLL) is the most common leukemia among
adults. The prognosis of CLL patients varies considerably. Transfer RNA-derived RNA …

Glutaminase isoforms expression switches microRNA levels and oxidative status in glioblastoma cells

J de Los Santos-Jiménez… - Journal of biomedical …, 2021 - Springer
Background Glutaminase isoenzymes GLS and GLS2 play apparently opposing roles in
cancer: GLS acts as an oncoprotein, while GLS2 (GAB isoform) has context specific tumour …

Dietary delphinidin inhibits human colorectal cancer metastasis associating with upregulation of miR-204-3p and suppression of the integrin/FAK axis

CC Huang, CH Hung, TW Hung, YC Lin, CJ Wang… - Scientific reports, 2019 - nature.com
Delphinidin is a flavonoid belonging to dietary anthocyanidin family that has been reported
to possess diverse anti-tumoral activities. However, the effects of delphinidin on colorectal …

Identification of a novel, internal tRNA-derived RNA fragment as a new prognostic and screening biomarker in chronic lymphocytic leukemia, using an innovative …

K Katsaraki, PI Artemaki, SG Papageorgiou, V Pappa… - Leukemia Research, 2019 - Elsevier
Chronic lymphocytic leukemia (CLL) is one of the most common types of leukemia in adults.
Several studies have identified various prognostic biomarkers in CLL. In this study, we …

Expression of non-coding RNAs in hematological malignancies

S Ghafouri-Fard, M Esmaeili, M Taheri - European Journal of …, 2020 - Elsevier
With the advent of novel high throughput techniques, an extensive number of non-coding
RNAs have been recognized to be involved in the pathogenesis of different types of …

A 3′ tRNA‐derived fragment produced by tRNALeuAAG and tRNALeuTAG is associated with poor prognosis in B‐cell chronic lymphocytic leukemia, independently …

K Katsaraki, PG Adamopoulos… - European Journal of …, 2021 - Wiley Online Library
Abstract Objective 3′ tRNA‐derived fragments (3′ tRFs) are important epigenetic
regulators in normal and pathological conditions. In this study, we aimed to explore the …

miRNA profile at diagnosis predicts treatment outcome in patients with B-chronic lymphocytic leukemia: A FILO study

I Duroux-Richard, AL Gagez, E Alaterre… - Frontiers in …, 2022 - frontiersin.org
During many years, chemo-immunotherapy fludarabine-cyclophosphamide-rituximab (FCR)
was the gold standard for first line treatment of medically fit patients with symptomatic B …