A review: Pharmacological aspects of metal based 1, 2, 4-triazole derived Schiff bases

W Zafar, SH Sumrra, ZH Chohan - European journal of medicinal chemistry, 2021 - Elsevier
Clinical reports have highlighted the radical increase of antibiotic resistance. As a result,
multidrug resistance has emerged as a serious threat to human health. Many organic …

Isatin derivatives and their anti-bacterial activities

H Guo - European Journal of Medicinal Chemistry, 2019 - Elsevier
Bacterial infections are account for the majority of hospital-acquired and community-
acquired infections. The emergency and widespread of drug-resistant pathogens has further …

Pharmacological aspects of schiff base metal complexes: A critical review

T Ashraf, B Ali, H Qayyum, MS Haroone… - Inorganic Chemistry …, 2023 - Elsevier
Multidrug-resistant infections have placed a financial and health burden on the health-care
system and population. As a result, human health was faced major issues due to multidrug …

A review on the biomedical efficacy of transition metal triazole compounds

SH Sumrra, W Zafar, M Imran… - Journal of Coordination …, 2022 - Taylor & Francis
From the apocalyptic era of antibiotic resistance, the scientific community around the world is
engaged in designing and developing metal-based compounds to inhibit and control …

Aminothiazole-linked metal chelates: synthesis, density functional theory, and antimicrobial studies with antioxidant correlations

S Noreen, SH Sumrra - ACS omega, 2021 - ACS Publications
During the current study, the new aminothiazole Schiff base ligands (S1) and (S2) were
designed by reacting 1, 3-thiazol-2-amine and 6-ethoxy-1, 3-benzothiazole-2-amine …

New 3d multifunctional metal chelates of sulfonamide: spectral, vibrational, molecular modeling, DFT, medicinal and in silico studies

AU Hassan, SH Sumrra, M Imran, ZH Chohan - Journal of Molecular …, 2022 - Elsevier
We are reporting a new synthetic design of sulfonamide entangled Schiff base ligands as H
2 L 1 and H 2 L 2 from 4-amino-N-(3-methyl-1, 2-oxazol-5-yl) benzene-1-sulfonamide and …

Exploring the bioactive sites of new sulfonamide metal chelates for multi-drug resistance: an experimental versus theoretical design

AU Hassan, SH Sumrra - … of Inorganic and Organometallic Polymers and …, 2022 - Springer
During this report, the synthesis, characterization, medicinal, and molecular modeling of
newly synthesized, bidentate sulfonamide metal (VO 2+, Co 2+, Ni 2+, Cu 2+, and Zn 2+) …

New organosulfur metallic compounds as potent drugs: synthesis, molecular modeling, spectral, antimicrobial, drug likeness and DFT analysis

AU Hassan, SH Sumrra, MN Zafar, MF Nazar… - Molecular Diversity, 2022 - Springer
During the present investigation, two new sulfonamide-based Schiff base ligands, 4-{[(2-
hydroxy-3-methoxyphenyl) methylidene] amino}-N-(1, 3-thiazol-2-yl) benzene-1-sulfonamid …

Spectroscopic and molecular electronic property investigation of 2-phenylpyrimidine-4, 6-diamine via 1H NMR, UV–vis, FT-Raman, FT-IR, and DFT approach

TO Unimuke, H Louis, W Emori, PS Idante… - Journal of Molecular …, 2022 - Elsevier
Abstract Herein, 2-phenylpyrimidine-4, 6-diamine (PPD) was selected to extensively
investigate its experimental, spectroscopic (FT-IR, FT-Raman, UV–vis, and 1 H NMR) and …

1, 2, 4-Triazole-quinoline/quinolone hybrids as potential anti-bacterial agents

J Zhang, S Wang, Y Ba, Z Xu - European journal of medicinal chemistry, 2019 - Elsevier
Bacterial infections, caused predominately by Gram-positive and Gram-negative organisms,
are proliferation of harmful strains of bacteria on or inside the body. Hospital-acquired and …