Flavonoids are one of the largest classes of small molecular secondary metabolites
produced in different parts of the plant. They display a wide range of pharmacological and …

Phenolic compounds and extracts with bioactive properties can be obtained from many
kinds of plant materials. These natural substances have gained attention in the food …

Leishmaniasis is a parasitic disease that presents four main clinical syndromes: cutaneous
leishmaniasis (CL), mucocutaneous leishmaniasis (MCL), visceral leishmaniasis/kala azar …

Endemic in 149 tropical and subtropical countries, neglected tropical diseases (NTDs) affect
more than 1 billion people annually, including 875 million children in developing …

The synthesis of secondary metabolites is a hallmark of plant defence against herbivores.
These compounds may be detrimental to consumers, but can also protect herbivores against …

Functionalized 4H‐chromenes represent one class of the most important structural scaffolds
in both synthetic and medicinal chemistry. They often appear in an arrange of biological …

Leishmaniasis is an infectious parasitic disease that is caused by protozoa of the genus
Leishmania, a member of the Trypanosomatidae family. Leishmaniasis is classified by the …

Leishmaniasis is a vector-borne neglected tropical disease caused by protozoan parasites
of the genus Leishmania for which there is a paucity of effective viable non-toxic drugs …

Infectious diseases caused by parasites are a major threat for the entire mankind, especially
in the tropics. More than 1 billion people world-wide are directly exposed to tropical …

Pharmacophore-based techniques currently are an integral part of many computer-aided
drug design workflows and have been successfully and extensively applied for tasks such …