Emerging studies across learning domains have shed light on mechanisms underlying
sleep's benefits during numerous developmental periods. In this conceptual review, we …

The memories that we retain can serve many functions. They guide our future actions, form a
scaffold for constructing the self, and continue to shape both the self and the way we …

Learning and plasticity rely on fine-tuned regulation of neuronal circuits during offline
periods. An unresolved puzzle is how the sleeping brain, in the absence of external …

Memory transformation is increasingly acknowledged in theoretical accounts of systems
consolidation, yet how memory quality and neural representation change over time and how …

Sleep is thought to support memory consolidation via reactivation of prior experiences, with
particular electrophysiological sleep signatures (slow oscillations (SOs) and sleep spindles) …

Hippocampal ripples are prominent synchronization events generated by hippocampal
neuronal assemblies. To date, ripples have been primarily associated with navigational …

Decades of rodent research have established the role of hippocampal sharp wave ripples
(SPW-Rs) in consolidating and guiding experience. More recently, intracranial recordings in …

Sleep is ubiquitous and essential, but its mechanisms remain unclear. Studies in animals
and humans have provided insights of sleep at vastly different spatiotemporal scales …

A hallmark of non-rapid eye movement sleep is the coordinated interplay of slow oscillations
(SOs) and sleep spindles. Traditionally, a cortico-thalamo-cortical loop is suggested to …

Sleep is assumed to be a unitary, global state in humans and most other animals that is
coordinated by executive centers in the brain stem, hypothalamus, and basal forebrain …