Steroid receptor interactions with heat shock protein and immunophilin chaperones

WB Pratt, DO Toft - Endocrine reviews, 1997 - academic.oup.com
I. Introduction II. 9S Receptors A. Estrogen receptors (ERs) B. Progesterone receptors (PRs)
C. Androgen receptors (ARs) D. Glucocorticoid receptors (GRs) E. Mineralocorticoid …

Regulation of signaling protein function and trafficking by the hsp90/hsp70-based chaperone machinery

WB Pratt, DO Toft - Experimental biology and medicine, 2003 - journals.sagepub.com
Nearly 100 proteins are known to be regulated by hsp90. Most of these substrates or “client
proteins” are involved in signal transduction, and they are brought into complex with hsp90 …

The 90-kDa molecular chaperone family: structure, function, and clinical applications. A comprehensive review

P Csermely, T Schnaider, C So, Z Prohászka… - Pharmacology & …, 1998 - Elsevier
The 90-kDa molecular chaperone family (which comprises, among other proteins, the 90-
kDa heat-shock protein, hsp90 and the 94-kDa glucose-regulated protein, grp94, major …

TPR proteins: the versatile helix

LD D'Andrea, L Regan - Trends in biochemical sciences, 2003 - cell.com
Tetratrico peptide repeat (TPR) proteins have several interesting properties, including their
folding characteristics, modular architecture and range of binding specificities. In the past …

[HTML][HTML] Hsp90: a specialized but essential protein-folding tool

JC Young, I Moarefi, FU Hartl - The Journal of cell biology, 2001 - ncbi.nlm.nih.gov
Hsp90 - PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI Homepage
MyNCBI Homepage Main Content Main Navigation Preview improvements coming to the …

Hsp90: structure and function

SE Jackson - Molecular chaperones, 2013 - Springer
Hsp90 is a highly abundant and ubiquitous molecular chaperone which plays an essential
role in many cellular processes including cell cycle control, cell survival, hormone and other …

Heat shock proteins: cellular and molecular mechanisms in the central nervous system

RA Stetler, Y Gan, W Zhang, AK Liou, Y Gao… - Progress in …, 2010 - Elsevier
Emerging evidence indicates that heat shock proteins (HSPs) are critical regulators in
normal neural physiological function as well as in cell stress responses. The functions of …

The FKBP51 glucocorticoid receptor co-chaperone: regulation, function, and implications in health and disease

GR Fries, NC Gassen, T Rein - International journal of molecular sciences, 2017 - mdpi.com
Among the chaperones and co-chaperones regulating the glucocorticoid receptor (GR),
FK506 binding protein (FKBP) 51 is the most intensely investigated across different …

Novel protein serine/threonine phosphatases: variety is the spice of life

PTW Cohen - Trends in biochemical sciences, 1997 - cell.com
The dephosphorylation of proteins on serine and threonine residues is a major mechanism
of cellular regulation. Many novel protein serine/threonine phosphatases in the PPP family …

Crosstalk in inflammation: the interplay of glucocorticoid receptor-based mechanisms and kinases and phosphatases

IME Beck, W Vanden Berghe, L Vermeulen… - Endocrine …, 2009 - academic.oup.com
Glucocorticoids (GCs) are steroidal ligands for the GC receptor (GR), which can function as
a ligand-activated transcription factor. These steroidal ligands and derivatives thereof are …