The electron-rich five-membered aromatic aza-heterocyclic imidazole, which contains two
nitrogen atoms, is an important functional fragment widely present in a large number of …

The tetrazole ring is an important pharmacophore. It is a structural component in many
drugs, drug candidates (or lead compounds) and various biochemical reagents. This review …

A series of novel aminopyrimidinyl benzimidazoles as potentially antimicrobial agents were
designed, synthesized and characterized by IR, NMR and HRMS spectra. The biological …

A series of novel 3-aminothiazolquinolones as analogues of quinolone antibacterial agents
were designed and synthesized in an effort to circumvent quinolone resistance. Among …

The increasing incidence of microbial resistance and newly emerging pathogens have
become a serious challenge for public health. More and more efforts have been directed to …

A series of aminothiazolyl norfloxacin analogues as a new type of potential antimicrobial
agents were synthesized and screened for their antimicrobial activities. Most of the prepared …

A novel series of benzimidazole-incorporated sulfonamide analogues were designed and
synthesized with an effort to overcome the increasing antibiotic resistance. Compound 5c …

This work did a new exploration towards aminothiazolquinolone oximes as potentially multi-
targeting antimicrobial agents. A class of novel hybrids of quinolone, aminothiazole …

Aminothiazolyl berberine derivatives as potentially antimicrobial agents were designed and
synthesized in an effort to overcome drug resistance. The antimicrobial assay revealed that …

In the recent past, prevalence of life threatening fungal diseases have increased rapidly in
immune-compromised cases such as acquired immunodeficiency syndrome (AIDS), cancer …