Molecular profiling for acromegaly treatment: a validation study

M Puig-Domingo, J Gil… - Endocrine-Related …, 2020 - erc.bioscientifica.com
Pharmacologic treatment of acromegaly is currently based upon assay-error strategy, the
first-generation somatostatin receptor ligands (SRL) being the first-line treatment. However …

HDAC11 is a novel regulator of fatty acid oxidative metabolism in skeletal muscle

E Hurtado, Y Núñez‐Álvarez, M Muñoz… - The FEBS …, 2021 - Wiley Online Library
Skeletal muscle is the largest tissue in mammalian organisms and is a key determinant of
basal metabolic rate and whole‐body energy metabolism. Histone deacetylase 11 …

MacroH2As regulate enhancer-promoter contacts affecting enhancer activity and sensitivity to inflammatory cytokines

D Corujo, R Malinverni, J Carrillo-Reixach, O Meers… - Cell reports, 2022 - cell.com
MacroH2A histone variants have a function in gene regulation that is poorly understood at
the molecular level. We report that macroH2A1. 2 and macroH2A2 modulate the …

Loss of HDAC11 accelerates skeletal muscle regeneration in mice

Y Núñez‐Álvarez, E Hurtado, M Munoz… - The FEBS …, 2021 - Wiley Online Library
Histone deacetylase 11 (HDAC11) is the latest identified member of the histone deacetylase
family of enzymes. It is highly expressed in brain, heart, testis, kidney, and skeletal muscle …

[PDF][PDF] The effects of chitosan nanoparticles on genes expression of artemisinin synthase in suspension culture of Artemisia annua L.: A comparative study

B Ghassemi, FD Nayeri, R Hosseini - Int. J. Adv. Biol. Biomed …, 2021 - academia.edu
Background: Despite significant efforts, the artemisinin-based drugs are still very expensive
due to the limited production of this metabolite within wild Artemisia spp. plants. Therefore …

Molecular determinants of enhanced response to somatostatin receptor ligands after debulking in large GH‐producing adenomas

J Gil, M Marques‐Pamies, M Jordà… - Clinical …, 2021 - Wiley Online Library
Objective Large somatotrophic adenomas depict poor response to somatostatin receptor
ligands (SRLs). Debulking has shown to enhance SRLs effect in some but not all cases and …

Kallikreins stepwise scoring reveals three subtypes of papillary thyroid cancer with prognostic implications

R Buj, I Mallona, A Diez-Villanueva, C Zafon, JL Mate… - Thyroid, 2018 - liebertpub.com
Background: Papillary thyroid cancer (PTC) is the most common type of thyroid cancer.
Unlike most cancers, its incidence has dramatically increased in the last decades mainly …

Enabling reproducible real-time quantitative PCR research: the RDML package

S Rödiger, M Burdukiewicz, AN Spiess… - …, 2017 - academic.oup.com
Motivation Reproducibility, a cornerstone of research, requires defined data formats, which
include the setup and output of experiments. The real-time PCR data markup language …

Molecular characterization of epithelial-mesenchymal transition and medical treatment related-genes in non-functioning pituitary neuroendocrine tumors

J Gil, M Marques-Pamies, E Valassi, G Serra… - Frontiers in …, 2023 - frontiersin.org
Introduction Different medical therapies have been developed for pituitary adenomas.
However, Non-Functioning Pituitary Neuroendocrine Tumors (NF-PitNET) have shown little …

[PDF][PDF] Влияние минорных антигенов гистосовместимости и полиморфизмов генов иммунных контрольных точек на иммунный ответ после трансплантации …

ДС Романюк - 2022 - blood.ru
Для терапии ряда опухолей гемопоэтической и лимфоидной ткани и некоторых
неопухолевых заболеваний кроветворной системы применяют трансплантацию …