Imaging flow cytometry combines the high-event-rate nature of flow cytometry with the
advantages of single-cell image acquisition associated with microscopy. The measurement …

Motile cilia are highly complex hair-like organelles of epithelial cells lining the surface of
various organ systems. Genetic mutations (usually with autosomal recessive inheritance) …

A finely regulated system of airway epithelial development governs the differentiation of
motile ciliated cells of the human respiratory tract, conferring the body's mucociliary …

Molecular mimicry between viral antigens and host proteins can produce cross-reacting
antibodies leading to autoimmunity. The coronavirus SARS-CoV-2 causes COVID-19, a …

Ciliopathies are a collection of disorders related to cilia dysfunction. Cilia are specialized
organelles that project from the surface of most cells. Motile and primary (sensory) cilia are …

Non-obstructive azoospermia (NOA) is the most severe form of male infertility and typically
incurable. Defining the genetic basis of NOA has proven challenging, and the most …

In 2019, a zoonotic coronavirus named severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) was identified as the causative agent of Coronavirus Disease 2019 (COVID …

Background Bronchiectasis can result from infectious, genetic, immunological and allergic
causes. 60–80% of cases are idiopathic, but a well-recognised genetic cause is the motile …

Primary ciliary dyskinesia (PCD) is a rare inherited condition affecting motile cilia and
leading to organ laterality defects, recurrent sino-pulmonary infections, bronchiectasis, and …

Multiciliated cells (MCC) project dozens to hundreds of motile cilia from the cell surface to
generate fluid flow across epithelial surfaces or turbulence to promote the transport of …