Mass spectrometry imaging for plant biology: a review

BA Boughton, D Thinagaran, D Sarabia, A Bacic… - Phytochemistry …, 2016 - Springer
Mass spectrometry imaging (MSI) is a developing technique to measure the spatio-temporal
distribution of many biomolecules in tissues. Over the preceding decade, MSI has been …

Mass spectrometry imaging in drug development

A Nilsson, RJA Goodwin, M Shariatgorji… - Analytical …, 2015 - ACS Publications
Drug discovery and development is a high-risk, expensive endeavor and it commonly takes
about 10− 15 years to obtain marketing approval from project inception. 1 Research efforts …

FDR-controlled metabolite annotation for high-resolution imaging mass spectrometry

A Palmer, P Phapale, I Chernyavsky, R Lavigne… - Nature …, 2017 - nature.com
High-mass-resolution imaging mass spectrometry promises to localize hundreds of
metabolites in tissues, cell cultures, and agar plates with cellular resolution, but it is …

Amphiphile nanoarchitectonics: from basic physical chemistry to advanced applications

M Ramanathan, LK Shrestha, T Mori, Q Ji… - Physical Chemistry …, 2013 - pubs.rsc.org
Amphiphiles, either synthetic or natural, are structurally simple molecules with the
unprecedented capacity to self-assemble into complex, hierarchical geometries in …

Online photochemical derivatization enables comprehensive mass spectrometric analysis of unsaturated phospholipid isomers

W Zhang, D Zhang, Q Chen, J Wu, Z Ouyang… - Nature …, 2019 - nature.com
Mass spectrometry-based lipidomics is the primary tool for the structural analysis of lipids but
the effective localization of carbon–carbon double bonds (C= C) in unsaturated lipids to …

Deep lipidomics and molecular imaging of unsaturated lipid isomers: a universal strategy initiated by mCPBA epoxidation

TH Kuo, HH Chung, HY Chang, CW Lin… - Analytical …, 2019 - ACS Publications
Cellular lipidome is highly regulated through lipogenesis, rendering diverse double-bond
positional isomers (C═ C isomer) of a given unsaturated lipid species. In recent years, there …

Evaluation of lipid coverage and high spatial resolution MALDI-imaging capabilities of oversampling combined with laser post-ionisation

AP Bowman, JFJ Bogie, JJA Hendriks, M Haidar… - Analytical and …, 2020 - Springer
Matrix-assisted laser desorption/ionisation-mass spectrometry imaging (MALDI-MSI) is a
powerful technique for visualising the spatial locations of lipids in biological tissues …

MALDI TOF imaging mass spectrometry in clinical pathology: a valuable tool for cancer diagnostics

J Kriegsmann, M Kriegsmann… - … journal of oncology, 2014 - spandidos-publications.com
Matrix-assisted laser desorption/ionization (MALDI) time-of-flight (TOF) imaging mass
spectrometry (IMS) is an evolving technique in cancer diagnostics and combines the …

Toward omics-scale quantitative mass spectrometry imaging of lipids in brain tissue using a multiclass internal standard mixture

M Vandenbosch, SM Mutuku, MJQ Mantas… - Analytical …, 2023 - ACS Publications
Mass spectrometry imaging (MSI) has accelerated our understanding of lipid metabolism
and spatial distribution in tissues and cells. However, few MSI studies have approached lipid …

Ambient mass spectrometry imaging using direct liquid extraction techniques

J Laskin, I Lanekoff - Analytical chemistry, 2016 - ACS Publications
Mass spectrometry imaging (MSI) is a powerful analytical technique that enables label-free
spatial localization and identification of molecules in complex samples. 1− 4 MSI …