[HTML][HTML] Automating the design-build-test-learn cycle towards next-generation bacterial cell factories

N Gurdo, DC Volke, D McCloskey, PI Nikel - New Biotechnology, 2023 - Elsevier
Automation is playing an increasingly significant role in synthetic biology. Groundbreaking
technologies, developed over the past 20 years, have enormously accelerated the …

Nobel Turing Challenge: creating the engine for scientific discovery

H Kitano - NPJ systems biology and applications, 2021 - nature.com
Scientific discovery has long been one of the central driving forces in our civilization. It
uncovered the principles of the world we live in, and enabled us to invent new technologies …

[HTML][HTML] Emerging Technologies in Medicine: Artificial Intelligence, Robotics, and Medical Automation

M Rezaei, S Saei, SJ Khouzani, ME Rostami… - Kindle, 2023 - preferpub.org
The healthcare industry is undergoing a profound transformation with the emergence of
revolutionary technologies like artificial intelligence (AI), robotics, and medical automation …

Building a biofoundry

MB Holowko, EK Frow, JC Reid, M Rourke… - Synthetic …, 2021 - academic.oup.com
A biofoundry provides automation and analytics infrastructure to support the engineering of
biological systems. It allows scientists to perform synthetic biology and aligned …

The smart SME technology readiness assessment methodology in the context of industry 4.0

SM Saad, R Bahadori, H Jafarnejad - Journal of Manufacturing …, 2021 - emerald.com
Purpose This study proposes the Smart SME Technology Readiness Assessment (SSTRA)
methodology which aims to enable practitioners to assess the SMEs Industry 4.0 technology …

[HTML][HTML] From genotypes to organisms: State-of-the-art and perspectives of a cornerstone in evolutionary dynamics

S Manrubia, JA Cuesta, J Aguirre, SE Ahnert… - Physics of Life …, 2021 - Elsevier
Understanding how genotypes map onto phenotypes, fitness, and eventually organisms is
arguably the next major missing piece in a fully predictive theory of evolution. We refer to this …

DNA-BOT: a low-cost, automated DNA assembly platform for synthetic biology

M Storch, MC Haines, GS Baldwin - Synthetic Biology, 2020 - academic.oup.com
Multi-part DNA assembly is the physical starting point for many projects in Synthetic and
Molecular Biology. The ability to explore a genetic design space by building extensive …

Understanding biological regulation through synthetic biology

CJ Bashor, JJ Collins - Annual review of biophysics, 2018 - annualreviews.org
Engineering synthetic gene regulatory circuits proceeds through iterative cycles of design,
building, and testing. Initial circuit designs must rely on often-incomplete models of …

Contextual dependencies expand the re-usability of genetic inverters

H Tas, L Grozinger, R Stoof, V de Lorenzo… - Nature …, 2021 - nature.com
The implementation of Boolean logic circuits in cells have become a very active field within
synthetic biology. Although these are mostly focussed on the genetic components alone, the …

Combinatorial metabolic pathway assembly approaches and toolkits for modular assembly

R Young, M Haines, M Storch, PS Freemont - Metabolic Engineering, 2021 - Elsevier
Synthetic Biology is a rapidly growing interdisciplinary field that is primarily built upon
foundational advances in molecular biology combined with engineering design principles …