Natural killer (NK) cells form a subset of lymphocytes that play a key role in immuno-
surveillance and host defense against cancer and viral infections. They recognize stressed …

First discovered in the 1980's, granulysin has until recently been thought of solely as an
effector molecule present within cytotoxic immune cell populations, and involved in the direct …

Phenotypic definition of helper ILC1 and NK cells is problematic due to overlapping markers.
Recently we showed the identification of cytotoxic ILC3s characterized by expression of …

Nk-lysins are antimicrobial proteins produced by cytotoxic T lymphocytes and natural killer
cells with a broad antimicrobial spectrum (including bacteria, fungi and parasites) …

Expansion microscopy (ExM) enables super-resolution fluorescence imaging on standard
microscopes by physical expansion of the sample. However, the investigation of interactions …

With the exception of mammals, vertebrate erythrocytes are nucleated. Nevertheless, these
cells are usually considered as mere carriers of hemoglobin. In this work, however, we …

Cytotoxic T lymphocytes (CTL) and Natural Killer (NK) cells utilize an overlapping effector
arsenal for the elimination of target cells. It was initially proposed that all cytotoxic effector …

Severe cutaneous adverse reactions (SCARs), such as Stevens-Johnson syndrome (SJS)
and toxic epidermal necrosis (TEN), are rare but life-threatening conditions induced mainly …

Lysosome‐related secretory organelles combine metabolic functions of conventional
lysosomes with an inducible secretory potential. Specialized variants of such bi‐functional …

Osteoarthritis (OA) is a chronic joint disease caused by mechanical damage and metabolic
factors that support the development of low‑grade inflammation. Increased levels of T helper …