[HTML][HTML] Solid lipid nanoparticles for drug delivery: pharmacological and biopharmaceutical aspects

S Scioli Montoto, G Muraca, ME Ruiz - Frontiers in molecular …, 2020 - frontiersin.org
In the golden age of pharmaceutical nanocarriers, we are witnessing a maturation stage of
the original concepts and ideas. There is no doubt that nanoformulations are extremely …

Using the quality by design (QbD) approach to optimize formulations of lipid nanoparticles and nanoemulsions: A review

S Cunha, CP Costa, JN Moreira, JMS Lobo… - … , Biology and Medicine, 2020 - Elsevier
Abstract Quality-by-design (QbD) approach has been applied to optimize lipid-based
nanosystems formulations, including solid lipid nanoparticles (SLN), nanostructured lipid …

Biomaterials in treatment of Alzheimer's disease

M Agrawal, E Prathyusha, H Ahmed, SK Dubey… - Neurochemistry …, 2021 - Elsevier
Alzheimer's disease (AD) is a non-recoverable progressive neurodegenerative disorder
most prevalent but not limited to the old age population. After all the scientific efforts, there …

Improvement of memory deficits in the rat model of Alzheimer's disease by erythropoietin-loaded solid lipid nanoparticles

T Dara, A Vatanara, M Sharifzadeh, S Khani… - Neurobiology of learning …, 2019 - Elsevier
Erythropoietin (EPO), a hematopoietic factor, is one of the promising neuroprotective
candidates in neurodegenerative disorders such as Alzheimer's disease (AD). Due to the …

Formulation and evaluation of kaempferol loaded nanoparticles against experimentally induced hepatocellular carcinoma: in vitro and in vivo studies

I Kazmi, FA Al-Abbasi, M Afzal, HN Altayb, MS Nadeem… - Pharmaceutics, 2021 - mdpi.com
The present study was designed to prepare Kaempferol loaded nanoparticles (KFP-Np) and
evaluate hepatoprotective and antioxidant effects in hepatocellular carcinoma models. KFP …

Representations of lipid nanoparticles using large language models for transfection efficiency prediction

S Moayedpour, J Broadbent, S Riahi, M Bailey… - …, 2024 - academic.oup.com
Abstract Motivation Lipid nanoparticles (LNPs) are the most widely used vehicles for mRNA
vaccine delivery. The structure of the lipids composing the LNPs can have a major impact on …

Advancements in the Application of Nanomedicine in Alzheimer's Disease: A Therapeutic Perspective

N Puranik, D Yadav, M Song - International Journal of Molecular Sciences, 2023 - mdpi.com
Alzheimer's disease (AD) is a progressive neurodegenerative disease that affects most
people worldwide. AD is a complex central nervous system disorder. Several drugs have …

Potential of hybrid lecithin-chitosan kaempferol ethosomes for the treatment of diabetic foot ulcer: In vitro and In vivo investigation

SS Raghav, B Kumar, NK Sethiya, M Singhal… - Journal of Drug Delivery …, 2024 - Elsevier
Hybrid lecithin-chitosan (LC) ethosomes were developed for maximizing encapsulation
efficiency and release of Kaempferol (KMP) in controlled effect for topical delivery. The …

New Insight for Enhanced Topical Targeting of Caffeine for Effective Cellulite Treatment: In Vitro Characterization, Permeation Studies, and Histological Evaluation in …

SA Fouad, TA Badr, A Abdelbary, M Fadel… - AAPS …, 2024 - Springer
Cellulite (CLT) is one of the commonly known lipodystrophy syndromes affecting post-
adolescent women worldwide. It is topographically characterized by an orange-peel …

Application of supramolecular technology for the delivery of erythropoietin: Synthesis of β-cyclodextrin-erythropoietin inclusion complex via a host-guest interaction

B Alizadeh, A Zarghi, R Aboofazeli… - Journal of Drug Delivery …, 2023 - Elsevier
Recombinant human erythropoietin (rhEPO) is an important therapeutic protein that is used
to treat anemia. To improve the pharmacokinetic properties of proteins, structure …