The recent epidemics of metabolic diseases, obesity, type 2 diabetes (T2D), liver lipid
disorders and metabolic syndrome have largely been attributed to genetic background and …

Persistent organic pollutants (POPs) are lipophilic compounds that travel with lipids and
accumulate mainly in adipose tissue. Recent human evidence links low-dose POPs to an …

We examine the role of adipose tissue, typically considered an energy storage site, as a
potential site of toxicant accumulation. Although the production of most persistent organic …

The purpose of this study was to review the epidemiological and experimental evidence
linking background exposure to a selection of environmental endocrine-disrupting …

The aryl hydrocarbon receptor (AhR) is a ligand-activated transcriptional factor that mediates
the toxicities of several environmental pollutants. Decades of research have been carried …

Although low doses of persistent organic pollutants (POPs), strong lipophilic chemicals with
long half‐lives, have been linked to various endocrine, immune, nervous and reproductive …

Diabetes mellitus is a major public health problem in all countries due to its high human and
economic burden. Major metabolic alterations are associated with the chronic …

Persistent organic pollutants (POPs) are a diverse family of contaminants that show
widespread global dispersion and bioaccumulation. Humans are continuously exposed to …

Type 2 diabetes prevalence is increasing dramatically across the globe, imposing a
tremendous toll on individuals and healthcare systems. Reversing these trends requires …

The molecular mechanisms underlying diet-induced obesity are complex and remain
unclear. The activation of the aryl hydrocarbon receptor (AhR), a xenobiotic sensor, by …