The Mycobacterium tuberculosis cell envelope has been evolving over time to make the
bacterium transmissible and adaptable to the human host. In this context, the M. tuberculosis …

The past few years have been very productive concerning the identification of genes
associated with leprosy. Candidate gene strategies using both case–control and family …

Although phthiocerol dimycocerosates (DIM) are major virulence factors of Mycobacterium
tuberculosis (Mtb), the causative agent of human tuberculosis, little is known about their …

Mycobacterium lepromatosis is an uncultured human pathogen associated with diffuse
lepromatous leprosy and a reactional state known as Lucio's phenomenon. By using deep …

Leprosy provides a model to investigate mechanisms of immune regulation in humans,
given that the disease forms a spectrum of clinical presentations that correlate with host …

Mycobacterium leprae causes leprosy and is unique among mycobacterial diseases in
producing peripheral neuropathy. This debilitating morbidity is attributed to axon …

Although leprosy (Hansen's disease) is one of the oldest known diseases, the pathogenicity
of Mycobacterium leprae (M. leprae) remains enigmatic. Indeed, the cell wall components …

This review is the sixth update of the original article published in 1999 on the application of
MALDI mass spectrometry to the analysis of carbohydrates and glycoconjugates and brings …

PGL-I (phenolic glycolipid I) emerged in the early 1980s on the one hand as part of intensive
efforts to define the typing antigens of a host of Mycobacterium spp. and also from …

The compositional and architectural complexity of the mycobacterial cell envelope is
probably the most distinctive feature of the Mycobacterium genus. It is the basis of many of …