[PDF][PDF] Altered connectivity in depression: GABA and glutamate neurotransmitter deficits and reversal by novel treatments
The mechanisms underlying the pathophysiology and treatment of depression and stress-
related disorders remain unclear, but studies in depressed patients and rodent models are …
related disorders remain unclear, but studies in depressed patients and rodent models are …
Prefrontal cortex circuits in depression and anxiety: contribution of discrete neuronal populations and target regions
Our understanding of depression and its treatment has advanced with the advent of
ketamine as a rapid-acting antidepressant and the development and refinement of tools …
ketamine as a rapid-acting antidepressant and the development and refinement of tools …
[HTML][HTML] Sex differences in stress-related alcohol use
MKR Peltier, TL Verplaetse, YS Mineur, IL Petrakis… - Neurobiology of …, 2019 - Elsevier
Rates of alcohol use disorder (AUD) have increased in women by 84% over the past ten
years relative to a 35% increase in men. This substantive increase in female drinking is …
years relative to a 35% increase in men. This substantive increase in female drinking is …
[HTML][HTML] Probiotics, prebiotics and postbiotics on mitigation of depression symptoms: Modulation of the brain–gut–microbiome axis
A Chudzik, A Orzyłowska, R Rola, GJ Stanisz - Biomolecules, 2021 - mdpi.com
The brain–gut–microbiome axis is a bidirectional communication pathway between the gut
microbiota and the central nervous system. The growing interest in the gut microbiota and …
microbiota and the central nervous system. The growing interest in the gut microbiota and …
[HTML][HTML] Cortical GABAergic dysfunction in stress and depression: new insights for therapeutic interventions
Major depressive disorder (MDD) is a debilitating illness characterized by neuroanatomical
and functional alterations in limbic structures, notably the prefrontal cortex (PFC), that can be …
and functional alterations in limbic structures, notably the prefrontal cortex (PFC), that can be …
Altered GABA-mediated information processing and cognitive dysfunctions in depression and other brain disorders
Cognitive dysfunctions, including impaired attention, learning, memory, planning and
problem solving, occur in depressive episodes, often persist during remission, predict …
problem solving, occur in depressive episodes, often persist during remission, predict …
Targeting glutamate signalling in depression: progress and prospects
Major depressive disorder (MDD) is severely disabling, and current treatments have limited
efficacy. The glutamate N-methyl-d-aspartate receptor (NMDAR) antagonist ketamine was …
efficacy. The glutamate N-methyl-d-aspartate receptor (NMDAR) antagonist ketamine was …
Glutamate and gamma-aminobutyric acid systems in the pathophysiology of major depression and antidepressant response to ketamine
In patients with major depressive disorder or bipolar disorder, abnormalities in excitatory
and/or inhibitory neurotransmission and neuronal plasticity may lead to aberrant functional …
and/or inhibitory neurotransmission and neuronal plasticity may lead to aberrant functional …
[HTML][HTML] Glutamate and GABA homeostasis and neurometabolism in major depressive disorder
Major depressive disorder (MDD) is a leading cause of distress, disability, and suicides. As
per the latest WHO report, MDD affects more than 260 million people worldwide. Despite …
per the latest WHO report, MDD affects more than 260 million people worldwide. Despite …
Prevalencia, causas y tratamiento de la depresión Mayor
EA Pérez-Padilla, VM Cervantes-Ramírez… - Revista …, 2017 - scielo.org.mx
La depresión mayor representa un problema de salud pública debido a su alta prevalencia.
La etiología de la depresión es compleja ya que en ella intervienen factores psicosociales …
La etiología de la depresión es compleja ya que en ella intervienen factores psicosociales …