Regular physical activity improves cardiometabolic and musculoskeletal health, helps with
weight management, improves cognitive and psychosocial functioning, and is associated …

One aspect of skeletal muscle memory is the ability of a previously trained muscle to
hypertrophy more rapidly following a period of detraining. Although the molecular basis of …

Aims/hypothesis A comprehensive assessment of skeletal muscle ultrastructure and
mitochondrial bioenergetics has not been undertaken in individuals with type 1 diabetes …

Abstract Kinesin-1 and Growth Associated Protein 43 (GAP-43) localization in muscle fiber
are crucial for proper skeletal muscle hypertrophy. To evaluate this assumption, we …

Diabetes mellitus is one of the most common metabolic diseases spread all over the world,
which results in hyperglycemia caused by the breakdown of insulin secretion or insulin …

We propose a mechanistic model for the development of diabetic myopathy based on the
human findings to date. This model suggests that repeated insulin injections in those with …

• Impairments to skeletal muscle health in T1D are, in many ways, similar to that observed in
the muscle of aged individuals, but are occurring at a younger age in T1D.• Mitochondrial …

Successful muscle regeneration following injury is essential for functional homeostasis of
skeletal muscles. Krüppel-like factor 15 (KLF15) is a metabolic transcriptional regulator in …

Diabetes represents a major public health concern with a considerable impact on human life
and healthcare expenditures. It is now well established that diabetes is characterized by a …

Lipocalin-2 (LCN2) is an adipokine previously described for its contribution to numerous
processes, including innate immunity and energy metabolism. LCN2 has also been …