Consensus Guidance for Monitoring Individuals With Islet Autoantibody–Positive Pre-Stage 3 Type 1 Diabetes

M Phillip, P Achenbach, A Addala… - Diabetes …, 2024 - diabetesjournals.org
Given the proven benefits of screening to reduce diabetic ketoacidosis (DKA) likelihood at
the time of stage 3 type 1 diabetes diagnosis, and emerging availability of therapy to delay …

Untangling the genetics of beta cell dysfunction and death in type 1 diabetes

CC Robertson, RM Elgamal, BA Henry-Kanarek… - Molecular …, 2024 - Elsevier
Abstract Type 1 diabetes (T1D) is a complex multi-system disease which arises from both
environmental and genetic factors, resulting in the destruction of insulin-producing …

Childhood screening for type 1 diabetes comparing automated multiplex Antibody Detection by Agglutination-PCR (ADAP) with single plex islet autoantibody …

A Lind, E Freyhult, F de Jesus Cortez, A Ramelius… - …, 2024 - thelancet.com
Background Two or more autoantibodies against either insulin (IAA), glutamic acid
decarboxylase (GADA), islet antigen-2 (IA-2A) or zinc transporter 8 (ZnT8A) denote stage 1 …

HLA Class II (DR, DQ, DP) Genes Were Separately Associated With the Progression From Seroconversion to Onset of Type 1 Diabetes Among Participants in Two …

LP Zhao, GK Papadopoulos, JS Skyler… - Diabetes …, 2024 - Am Diabetes Assoc
OBJECTIVE To explore associations of HLA class II genes (HLAII) with the progression of
islet autoimmunity from asymptomatic to symptomatic type 1 diabetes (T1D). RESEARCH …

A multi-ancestry genome-wide association study in type 1 diabetes

DA Michalek, C Tern, W Zhou… - Human Molecular …, 2024 - academic.oup.com
Abstract Type 1 diabetes (T1D) is an autoimmune disease caused by destruction of the
pancreatic β-cells. Genome-wide association (GWAS) and fine mapping studies have been …

Family History of Diabetes and Clinical Characteristics in Children at Diagnosis of Type 1 Diabetes—A Swedish Population-Based Study

E Hedlund, J Tojjar, L Lilja, H Elding Larsson… - Diabetes …, 2024 - diabetesjournals.org
OBJECTIVE To compare the prevalence of parental diabetes between children with and
without type 1 diabetes (T1D), and to compare clinical characteristics at diagnosis of T1D in …

A Bioartificial Pancreas with “Immune Stealth” and Continuous Oxygen Supply for Islet Transplantation

Y Zheng, W Yang, W Gao, X Zhang… - Macromolecular …, 2023 - Wiley Online Library
Transplantation of microencapsulated islet cells remains a promising strategy for the
normalization of glucose metabolism control in type 1 diabetes mellitus. However, vigorous …

1 型糖尿病小鼠肠道菌群与免疫状态演变的实验研究.

黄宝江, 林小雅, 张军, 郭松, 李燕虹… - Chinese Journal of …, 2024 - search.ebscohost.com
目的探究链脲佐菌素(STZ) 诱导的1 型糖尿病(T1DM) 小鼠在不同时期的肠道功能,
血清相关抗体, 脾脏细胞因子谱表达与肠道菌群的演变. 方法取3~ 4 周龄雄性C57BL/6 小鼠28 …

[PDF][PDF] Decoding Peptide-MHC Recognition to unravel T cell involvement in Type 1 Diabetes and allogeneic

M Göransson - Medicine, 2019 - orbit.dtu.dk
This thesis was submitted to the Technical University of Denmark, Department of Health
Technology, as partial fulfillment to obtain a PhD degree. Research activities were …