Abstract Type 1 diabetes (T1D) is a complex multi-system disease which arises from both environmental and genetic factors, resulting in the destruction of insulin-producing …
A Lind, E Freyhult, F de Jesus Cortez, A Ramelius… - …, 2024 - thelancet.com
Background Two or more autoantibodies against either insulin (IAA), glutamic acid decarboxylase (GADA), islet antigen-2 (IA-2A) or zinc transporter 8 (ZnT8A) denote stage 1 …
OBJECTIVE To explore associations of HLA class II genes (HLAII) with the progression of islet autoimmunity from asymptomatic to symptomatic type 1 diabetes (T1D). RESEARCH …
DA Michalek, C Tern, W Zhou… - Human Molecular …, 2024 - academic.oup.com
Abstract Type 1 diabetes (T1D) is an autoimmune disease caused by destruction of the pancreatic β-cells. Genome-wide association (GWAS) and fine mapping studies have been …
E Hedlund, J Tojjar, L Lilja, H Elding Larsson… - Diabetes …, 2024 - diabetesjournals.org
OBJECTIVE To compare the prevalence of parental diabetes between children with and without type 1 diabetes (T1D), and to compare clinical characteristics at diagnosis of T1D in …
Y Zheng, W Yang, W Gao, X Zhang… - Macromolecular …, 2023 - Wiley Online Library
Transplantation of microencapsulated islet cells remains a promising strategy for the normalization of glucose metabolism control in type 1 diabetes mellitus. However, vigorous …
This thesis was submitted to the Technical University of Denmark, Department of Health Technology, as partial fulfillment to obtain a PhD degree. Research activities were …