In silico model-guided identification of transcriptional regulator targets for efficient strain design

L Koduru, M Lakshmanan, DY Lee - Microbial cell factories, 2018 - Springer
Background Cellular metabolism is tightly regulated by hard-wired multiple layers of
biological processes to achieve robust and homeostatic states given the limited resources …

Genome-Scale In Silico Analysis for Enhanced Production of Succinic Acid in Zymomonas mobilis

H Widiastuti, NR Lee, IA Karimi, DY Lee - Processes, 2018 - mdpi.com
Presented herein is a model-driven strategy for characterizing the production capability of
expression host and subsequently identifying targets for strain improvement by resorting to …

A new strategy for dynamic metabolic flux estimation by integrating transient metabolome data into genome-scale metabolic models

P Liu, Y Hua, W Zhang, T Xie, Y Zhuang, J Xia… - Bioprocess and …, 2021 - Springer
Metabolic flux analysis (MFA) is a powerful tool for studying microbial cell physiology.
Isotope-based MFA is the accepted standard for studying metabolic fluxes under steady …

Autotrophy and Mixotrophy in Chlamydomonas Reinhardtii: The Impact of Acetate on Metabolism and Light Enhanced Respiration

JL Oliver - 2024 - search.proquest.com
Photosynthetic organisms generate ATP via the chloroplast and mitochondrial electron
transport chains (ETCs). Electron flow through linear and alternative pathways is modified in …

Metabolische Analysen zur Herstellung aromatischer Aminosäuren mit Escherichia coli im Zulaufverfahren

JM Tröndle - 2019 - mediatum.ub.tum.de
Parallele Kurzzeitexperimente mit unterschiedlichen Substraten wurden zur
Charakterisierung des Stoffwechsels rekombinanter E. coli aus Zulaufverfahren zur …