A review on the green synthesis of benzimidazole derivatives and their pharmacological activities

M Nardi, NCH Cano, S Simeonov, R Bence, A Kurutos… - Catalysts, 2023 - mdpi.com
Benzimidazoles and their derivatives play an extraordinarily significant role as therapeutic
agents, eg, antiulcer, analgesic, and anthelmintic drugs. The organic synthesis of …

Synthesis and evaluation of selected benzimidazole derivatives as potential antimicrobial agents

FAS Alasmary, AM Snelling, ME Zain, AM Alafeefy… - Molecules, 2015 - mdpi.com
A library of 53 benzimidazole derivatives, with substituents at positions 1, 2 and 5, were
synthesized and screened against a series of reference strains of bacteria and fungi of …

Green synthesis of privileged benzimidazole scaffolds using active deep eutectic solvent

ML Di Gioia, R Cassano, P Costanzo, N Herrera Cano… - Molecules, 2019 - mdpi.com
The exploitation and use of alternative synthetic methods, in the face of classical procedures
that do not conform to the ethics of green chemistry, represent an ever-present problem in …

Simple and efficient protocol for the synthesis of benzoxazole, benzoimidazole and benzothiazole heterocycles using Fe (III)–Schiff base/SBA-15 as a nanocatalyst

GR Bardajee, M Mohammadi, H Yari, A Ghaedi - Chinese Chemical Letters, 2016 - Elsevier
Benzimidazoles, benzoxazoles, and benzothiazoles derivatives were synthesized from
condensation of aldehydes and 1, 2-phenylenediamine or ortho-aminophenol or ortho …

Experimental and theoretical approving of anomeric based oxidation in the preparation of 2-sbstituted benz-(imida, oxa and othia)-zoles using [2, 6-DMPy-NO 2] C …

MA Zolfigol, A Khazaei, S Alaie, S Baghery, F Maleki… - RSC …, 2016 - pubs.rsc.org
The synthesis of 2-sbstituted benz-(imida, oxa and othia)-zole derivatives were occurred in
the presence of 2, 6-dimethyl-1-nitropyridin-1-ium trinitromethanide [2, 6-DMPy-NO2] C …

[HTML][HTML] Facile and efficient method for synthesis of benzimidazole derivatives catalyzed by zinc triflate

R Srinivasulu, KR Kumar… - Green and Sustainable …, 2014 - scirp.org
We report the synthesis of benzimidazole derivatives using zinc triflate as an efficient
catalyst. One-pot synthesis of 2-substituted benzimidazole derivatives from o …

[BMPTFB]-ionic liquid as an efficient catalyst for the rapid, and eco-friendly synthesis of benzimidazole, 2-substituted benzimidazole, and benzothiazole derivatives at …

BB Popatkar, NA Sasane… - Synthetic Communications, 2022 - Taylor & Francis
We wish to report an easy, mild, and effective procedure for the synthesis of benzimidazole,
2-substituted benzimidazole, and benzothiazole derivatives by employing 1-butyl-1 …

NaHSO4‐SiO2‐Promoted Solvent‐Free Synthesis of Benzoxazoles, Benzimidazoles, and Benzothiazole Derivatives

KR Kumar, PVV Satyanarayana… - Journal of …, 2013 - Wiley Online Library
An efficient protocol has been developed for the preparation of a library of benzoxazole,
benzimidazole, and benzothiazole derivatives from reactions of acyl chlorides with o …

Unexpected synthesis, single-crystal x-ray structure, anticancer activity, and molecular docking studies of certain 2–((imidazole/benzimidazol–2–yl) thio)–1 …

T Al-Warhi, MA Said, MA El Hassab, N Aljaeed… - Crystals, 2020 - mdpi.com
In connection with our research program concerning development of novel effective
benzimidazole-based anticancer candidates, herein we describe a new unexpected …

1, 4-Diazabicyclo [2.2. 2] octanium diacetate: An effective, mild and reusable catalyst for the synthesis of 2, 4, 5–trisubstituted imidazoles

L Zare Fekri, M Nateghi - Chemical Review and Letters, 2021 - chemrevlett.com
1, 4-Diazabicyclo [2.2. 2] octanium diacetate supplies an environmentally friendly procedure
for the synthesis of 2, 4, 5-trisubstituted imidazoles through one-pot multicomponent …