Objective: To evaluate the literature and identify important aspects of insulin therapy that
facilitate safe and effective infusion therapy for a defined glycemic end point. Methods:

Results of randomised controlled trials of tight glycaemic control in hospital inpatients might
vary with population and disease state. Individualised therapy for different hospital inpatient …

Diabetes and ischaemic stroke often arise together. People with diabetes have more than
double the risk of ischaemic stroke after correction for other risk factors, relative to …

Patients with acute ischemic stroke frequently test positive for hyperglycemia, which is
associated with a poor clinical outcome. This association between poor glycemic control and …

Background: The benefits and harms of intensive insulin therapy (IIT) titrated to strict
glycemic targets in hospitalized patients remain uncertain. Purpose: To evaluate the benefits …

Objectives: To examine the predisposing factors for hypoglycemia in medical-surgical
intensive care unit patients treated with intensive insulin therapy and to assess its …

OBJECTIVE Tight glycemic control (TGC) in critically ill patients is associated with an
increased risk of hypoglycemia. Whether those short episodes of hypoglycemia are …

Background The development of renal and liver dysfunction may be accompanied by initially
subtle derangements in the gluconeogenetic function. Discrepantly low glucose levels …

Introduction The purpose of this research is to provide recommendations for the
management of glycemic control in critically ill patients. Methods Twenty-one experts issued …

Background: The management of critically ill hyperglycemic patients in the intensive care
unit (ICU) has been fraught with recent controversy. Only one randomized trial has …