Haemolytic Disease of the Fetus and Newborn (HDFN) is caused by maternal
alloimmunization against red blood cell antigens. In severe cases, HDFN may lead to fetal …

Birth defects are an urgent global health priority. They affect millions of births worldwide. But
their prevalence and impact are largely under-ascertained, particularly in middle-and low …

Background Transfusions are the primary therapy for thalassemia but have significant
cumulative risks. In 2004, the C enters for D isease C ontrol and P revention (CDC) …

Background Universal screening of all antenatal women, including D antigen-positive
pregnant ones, is mandatory in most developed countries. However, no guidelines on this …

BACKGROUND: Transfusion recipients who become alloimmunized to red cell or platelet
(PLT) antigens require antigen‐negative blood to limit adverse transfusion reactions. Blood …

目的: 调查中国汉族患者人群中红细胞血型不规则抗体的检出率及各种特异性不规则抗体的分布
特点. 方法: 选取在我院就诊的来自中国不同行政区域汉族患者30800 (男16563, 女14237) …

BACKGROUND: Several irregular red blood cell alloantibodies, produced by
alloimmunization of antigens in transfusions or pregnancies, have clinical importance …

OBJECTIVE: There is limited information published about anti-E alloimmunization. We
review our experience at The Ohio State University to determine appropriate management …

Background Maternal red cell IgG antibodies can cross the placenta and cause hemolysis of
fetal red cells in case of antigenic differences between maternal and fetal RBCs, leading to …

BACKGROUND There has yet to be a comprehensive analysis of blood group antigen
prevalence in Asian Americans and Native Americans. There may be ethnic differences in …