Super enhancers—Functional cores under the 3D genome
Complex biochemical reactions take place in the nucleus all the time. Transcription
machines must follow the rules. The chromatin state, especially the three‐dimensional …
machines must follow the rules. The chromatin state, especially the three‐dimensional …
Identification of platform-independent diagnostic biomarker panel for hepatocellular carcinoma using large-scale transcriptomics data
The high mortality rate of hepatocellular carcinoma (HCC) is primarily due to its late
diagnosis. In the past, numerous attempts have been made to design genetic biomarkers for …
diagnosis. In the past, numerous attempts have been made to design genetic biomarkers for …
[HTML][HTML] CancerEnD: a database of cancer associated enhancers
CancerEnD is an integrated resource developed for annotating 8524 unique expressed
enhancers, associated genes, somatic mutations and copy number variations of 8063 …
enhancers, associated genes, somatic mutations and copy number variations of 8063 …
Identification of prognostic biomarkers for major subtypes of non-small-cell lung cancer using genomic and clinical data
Purpose Intra-tumor heterogeneity and high mortality among patients with non-small-cell
lung carcinoma (NSCLC) emphasize the need to identify reliable prognostic markers unique …
lung carcinoma (NSCLC) emphasize the need to identify reliable prognostic markers unique …
In silico and in vivo anti-angiogenic validation on ethanolic extract of Curcuma longa and curcumin compound in hepatocellular carcinoma through mitogen activated …
Hepatocellular carcinoma (HCC) is the most frequent primary malignancy of the liver. The
aim of this study is to evaluate the comparative in silico and in vivo ameliorative potential of …
aim of this study is to evaluate the comparative in silico and in vivo ameliorative potential of …
Identifying enhancer-driven subtype-specific prognostic markers in breast cancer based on multi-omics data
H Zhao, S Zhang, X Yin, C Zhang, L Wang… - Frontiers in …, 2022 - frontiersin.org
Breast cancer is a cancer of high complexity and heterogeneity, with differences in
prognosis and survival among patients of different subtypes. Copy number variations …
prognosis and survival among patients of different subtypes. Copy number variations …
[HTML][HTML] Identification of hub genes and their novel diagnostic and prognostic significance in pancreatic adenocarcinoma
D Zuo, Y Chen, X Zhang, Z Wang, W Jiang… - Cancer Biology & …, 2022 - ncbi.nlm.nih.gov
Objective: The main reasons for the poor prognoses of pancreatic adenocarcinoma (PA)
patients are rapid early-stage progression, advanced stage metastasis, and chemotherapy …
patients are rapid early-stage progression, advanced stage metastasis, and chemotherapy …
Journey through Genomic and Transcriptomic Analyses to Understand Gene Expression-Time for Enhancer RNAs
A Grenda, P Krawczyk - Critical Reviews™ in Eukaryotic Gene …, 2021 - dl.begellhouse.com
Genome analyses using next-generation sequencing are providing more and more
information on DNA sequences. However, there is a trend towards the return to RNA …
information on DNA sequences. However, there is a trend towards the return to RNA …
Development and validation of the trans-omics model for pancreatic adenocarcinoma
W Huang, W Weng, B Wu, T Ye, Z Lin, Z Zhang… - …, 2021 - Taylor & Francis
Aim: To develop a trans-omics-based molecular clinicopathological algorithm for predicting
pancreatic adenocarcinoma prognosis, we performed a comprehensive analysis of the …
pancreatic adenocarcinoma prognosis, we performed a comprehensive analysis of the …
Integrative multi-omics analysis reveals the landscape of Cyclin-Dependent Kinase (CDK) family genes in pan-cancer
P Wang, M Xie, D Yang, F Wang, E Chen - 2022 - researchsquare.com
Objective Cyclin-Dependent Kinases (CDKs) get widely involved in cancer development.
However, A wealth of conflicting data raise the question of whether CDKs serve as …
However, A wealth of conflicting data raise the question of whether CDKs serve as …