The biological and clinical significance of emerging SARS-CoV-2 variants
The past several months have witnessed the emergence of SARS-CoV-2 variants with novel
spike protein mutations that are influencing the epidemiological and clinical aspects of the …
spike protein mutations that are influencing the epidemiological and clinical aspects of the …
Structural biology of SARS-CoV-2: open the door for novel therapies
W Yan, Y Zheng, X Zeng, B He, W Cheng - Signal Transduction and …, 2022 - nature.com
Abstract Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is the causative
agent of the pandemic disease COVID-19, which is so far without efficacious treatment. The …
agent of the pandemic disease COVID-19, which is so far without efficacious treatment. The …
Neutralization of ba. 4–ba. 5, ba. 4.6, ba. 2.75. 2, bq. 1.1, and xbb. 1 with bivalent vaccine
J Zou, C Kurhade, S Patel, N Kitchin… - … England Journal of …, 2023 - Mass Medical Soc
Neutralization of BA.4–BA.5, BA.4.6, BA.2.75.2, BQ.1.1, and XBB.1 with Bivalent Vaccine |
NEJM Skip to main content NEJM Group Follow Us Facebook Twitter Instagram YouTube …
NEJM Skip to main content NEJM Group Follow Us Facebook Twitter Instagram YouTube …
An infectious SARS-CoV-2 B. 1.1. 529 Omicron virus escapes neutralization by therapeutic monoclonal antibodies
The emergence of the highly transmissible B. 1.1. 529 Omicron variant of severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) is concerning for antibody …
respiratory syndrome coronavirus 2 (SARS-CoV-2) is concerning for antibody …
[PDF][PDF] The Omicron variant is highly resistant against antibody-mediated neutralization: Implications for control of the COVID-19 pandemic
M Hoffmann, N Krüger, S Schulz, A Cossmann… - Cell, 2022 - cell.com
The rapid spread of the SARS-CoV-2 Omicron variant suggests that the virus might become
globally dominant. Further, the high number of mutations in the viral spike protein raised …
globally dominant. Further, the high number of mutations in the viral spike protein raised …
Neutralization of severe acute respiratory syndrome coronavirus 2 omicron variant by sera from BNT162b2 or CoronaVac vaccine recipients
Background The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) omicron
variant, designated as a variant of concern by the World Health Organization, carries …
variant, designated as a variant of concern by the World Health Organization, carries …
SARS-CoV-2 infection in free-ranging white-tailed deer
Humans have infected a wide range of animals with SARS-CoV-2,,,–, but the establishment
of a new natural animal reservoir has not been observed. Here we document that free …
of a new natural animal reservoir has not been observed. Here we document that free …
Omicron variant showed lower neutralizing sensitivity than other SARS-CoV-2 variants to immune sera elicited by vaccines after boost
J Ai, H Zhang, Y Zhang, K Lin, Y Zhang… - Emerging microbes & …, 2022 - Taylor & Francis
The emerging new VOC B. 1.1. 529 (Omicron) variant has raised serious concerns due to
multiple mutations, reported significant immune escape, and unprecedented rapid …
multiple mutations, reported significant immune escape, and unprecedented rapid …
[HTML][HTML] SARS-CoV-2 mRNA vaccines induce persistent human germinal centre responses
JS Turner, JA O'Halloran, E Kalaidina, W Kim… - Nature, 2021 - nature.com
Abstract SARS-CoV-2 mRNA-based vaccines are about 95% effective in preventing COVID-
19 1, 2, 3, 4, 5. The dynamics of antibody-secreting plasmablasts and germinal centre B …
19 1, 2, 3, 4, 5. The dynamics of antibody-secreting plasmablasts and germinal centre B …
[HTML][HTML] SARS-CoV-2 variants, spike mutations and immune escape
Although most mutations in the severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) genome are expected to be either deleterious and swiftly purged or relatively …
CoV-2) genome are expected to be either deleterious and swiftly purged or relatively …