Tissue inhibitors of metalloproteinases (TIMPs) are a conserved family of proteins that were
originally identified as endogenous inhibitors of matrixin and adamalysin endopeptidase …

Background: Fibroproliferative disorders result in excessive scar formation, are associated
with high morbidity, and cost billions of dollars every year. Of these, keloid disease presents …

Background and objectives Microneedling therapy is a widely used technique in
dermatology. However, little is known about the underlying molecular effects of this therapy …

Keloids are characterized by increased deposition of fibrous tissue in the skin and
subcutaneous tissue following an abnormal wound healing process. Although keloid …

Silver nanoparticles (AgNP) can migrate to tissues and cells of the body, as well as to
agglomerate, which reduces the effectiveness of their use for the antimicrobial protection of …

Keloids (KDs) and hypertrophic scars (HSs), two forms of pathological scars, seriously affect
the physical and psychological health of patients. Despite many similarities with HSs, KDs …

Introduction Keloids are excessive fibroproliferative diseases that are caused by abnormal
wound healing. The anti-proliferative activity of Physalis angulata compounds has potential …

Bulk Zn 1− x Co x O samples were synthesized via standard solid-state reaction route with
different Co molar concentrations up to 21%. A detailed microstructural analysis was carried …

Hypertrophic scars (HSs) and keloids are histologically characterized by excessive
extracellular matrix (ECM) deposition. ECM deposition depends on the balance between …

Methods and Results Compared with N-CM, H-CM not only strongly reduced cell viability
and increased apoptosis of human cervical cancer cells (HeLa cells), but also increased …