Infections are one of the major selective pressures acting on humans, and host-pathogen interactions contribute to shaping the genetic diversity of both organisms. Evolutionary …
Motivation: We present a new feature of the MAFFT multiple alignment program for suppressing over-alignment (aligning unrelated segments). Conventional MAFFT is highly …
K Katoh, DM Standley - Molecular biology and evolution, 2013 - academic.oup.com
We report a major update of the MAFFT multiple sequence alignment program. This version has several new features, including options for adding unaligned sequences into an existing …
RH Ali, M Bogusz, S Whelan - Molecular biology and evolution, 2019 - academic.oup.com
Multiple sequence alignment (MSA) is ubiquitous in evolution and bioinformatics. MSAs are usually taken to be a known and fixed quantity on which to perform downstream analysis …
T Hu, J Li, H Zhou, C Li, EC Holmes… - Briefings in …, 2021 - academic.oup.com
In early January 2020, the novel coronavirus (SARS-CoV-2) responsible for a pneumonia outbreak in Wuhan, China, was identified using next-generation sequencing (NGS) and …
A comprehensive account of both basic and advanced material in phylogeny estimation, focusing on computational and statistical issues. No background in biology or computer …
Multiple sequence alignment (MSA) is a key modeling procedure when analyzing biological sequences. Homology and evolutionary modeling are the most common applications of …
L Bromham - Trends in Ecology & Evolution, 2019 - cell.com
Confidence in molecular dating analyses has grown with the increasing sophistication of the methods. Some problematic cases where molecular dates disagreed with paleontological …
Molecular phylogenetic inference is inherently dependent on choices in both methodology and data. Many insightful studies have shown how choices in methodology, such as the …