Multiple sequence alignment modeling: methods and applications

M Chatzou, C Magis, JM Chang… - Briefings in …, 2016 - academic.oup.com
This review provides an overview on the development of Multiple sequence alignment
(MSA) methods and their main applications. It is focused on progress made over the past …

Evolutionary insights into host–pathogen interactions from mammalian sequence data

M Sironi, R Cagliani, D Forni, M Clerici - Nature Reviews Genetics, 2015 - nature.com
Infections are one of the major selective pressures acting on humans, and host-pathogen
interactions contribute to shaping the genetic diversity of both organisms. Evolutionary …

A simple method to control over-alignment in the MAFFT multiple sequence alignment program

K Katoh, DM Standley - Bioinformatics, 2016 - academic.oup.com
Motivation: We present a new feature of the MAFFT multiple alignment program for
suppressing over-alignment (aligning unrelated segments). Conventional MAFFT is highly …

MAFFT multiple sequence alignment software version 7: improvements in performance and usability

K Katoh, DM Standley - Molecular biology and evolution, 2013 - academic.oup.com
We report a major update of the MAFFT multiple sequence alignment program. This version
has several new features, including options for adding unaligned sequences into an existing …

Identifying clusters of high confidence homologies in multiple sequence alignments

RH Ali, M Bogusz, S Whelan - Molecular biology and evolution, 2019 - academic.oup.com
Multiple sequence alignment (MSA) is ubiquitous in evolution and bioinformatics. MSAs are
usually taken to be a known and fixed quantity on which to perform downstream analysis …

Bioinformatics resources for SARS-CoV-2 discovery and surveillance

T Hu, J Li, H Zhou, C Li, EC Holmes… - Briefings in …, 2021 - academic.oup.com
In early January 2020, the novel coronavirus (SARS-CoV-2) responsible for a pneumonia
outbreak in Wuhan, China, was identified using next-generation sequencing (NGS) and …

[图书][B] Computational phylogenetics: an introduction to designing methods for phylogeny estimation

T Warnow - 2018 - books.google.com
A comprehensive account of both basic and advanced material in phylogeny estimation,
focusing on computational and statistical issues. No background in biology or computer …

TCS: a new multiple sequence alignment reliability measure to estimate alignment accuracy and improve phylogenetic tree reconstruction

JM Chang, P Di Tommaso… - Molecular biology and …, 2014 - academic.oup.com
Multiple sequence alignment (MSA) is a key modeling procedure when analyzing biological
sequences. Homology and evolutionary modeling are the most common applications of …

Six impossible things before breakfast: assumptions, models, and belief in molecular dating

L Bromham - Trends in Ecology & Evolution, 2019 - cell.com
Confidence in molecular dating analyses has grown with the increasing sophistication of the
methods. Some problematic cases where molecular dates disagreed with paleontological …

A genome-scale investigation of how sequence, function, and tree-based gene properties influence phylogenetic inference

XX Shen, L Salichos, A Rokas - Genome Biology and Evolution, 2016 - academic.oup.com
Molecular phylogenetic inference is inherently dependent on choices in both methodology
and data. Many insightful studies have shown how choices in methodology, such as the …