Diverse populations of GABAA receptors (GABAARs) throughout the brain mediate fast
inhibitory transmission and are modulated by various endogenous ligands and therapeutic …

The heterogeneity of autoantibody targets in autoimmune encephalitides presents a
challenge for understanding cellular and humoral pathophysiology, and the development of …

γ-Aminobutiryc acid (GABA) is found extensively in different brain nuclei, including parts
involved in Parkinson's disease (PD), such as the basal ganglia and hippocampus. In PD …

Memory and cognitive impairment are the principal clinical symptoms of Alzheimer's disease
(AD). Cholinergic deficiency, amyloid-beta (Aβ) toxicity, tau protein hyperphosphorylation …

Despite the substantial contribution of disruptions in GABAergic inhibitory neurotransmission
to the etiology of psychiatric, neurodevelopmental, and neurodegenerative disorders …

Developing hippocampal neurons undergo rapid synaptogenesis in response to
neurotrophic signals to form and refine circuit connections. The adipokine leptin is a satiety …

Drugs directly targeting γ-aminobutyric acid type A receptors (GABA A Rs), the major
mediators of fast synaptic inhibition, contribute significantly to today's neuropharmacology …

Gephyrin has long been thought of as a master regulator for inhibitory synapses, acting as a
scaffold to organize γ-aminobutyric acid type A receptors (GABAARs) at the post-synaptic …

Triptolide is an epoxidized diterpene lactone isolated from Tripterygium wilfordii. Studies
have shown that triptolide exerts organ‐protective effects. However, it remains unknown …

The γ-aminobutyric acid type A receptor (GABA (A) receptor) is a membrane protein
activated by the neurotransmitter GABA. Structurally, this major inhibitory neurotransmitter …