Salivarian trypanosomosis: a review of parasites involved, their global distribution and their interaction with the innate and adaptive mammalian host immune system

M Radwanska, N Vereecke, V Deleeuw… - Frontiers in …, 2018 - frontiersin.org
Salivarian trypanosomes are single cell extracellular parasites that cause infections in a
wide range of hosts. Most pathogenic infections worldwide are caused by one of four major …

Passage of parasites across the blood-brain barrier

W Masocha, K Kristensson - Virulence, 2012 - Taylor & Francis
The blood-brain barrier (BBB) is a structural and functional barrier that protects the central
nervous system (CNS) from invasion by blood-borne pathogens including parasites …

Tryps and trips: cell trafficking across the 100-year-old blood–brain barrier

M Bentivoglio, K Kristensson - Trends in neurosciences, 2014 - cell.com
One hundred years ago, Edwin E. Goldmann discovered the blood–brain barrier (BBB)
using trypan dyes. These dyes were developed and named by Paul Ehrlich during his …

Early invasion of brain parenchyma by African trypanosomes

U Frevert, A Movila, OV Nikolskaia, J Raper… - 2012 - journals.plos.org
Human African trypanosomiasis or sleeping sickness is a vector-borne parasitic disease that
has a major impact on human health and welfare in sub-Saharan countries. Based mostly …

Development of a pHrodo-Based Assay for the Assessment of In Vitro and In Vivo Erythrophagocytosis during Experimental Trypanosomosis

B Stijlemans, J Cnops, P Naniima, A Vaast… - PLoS neglected …, 2015 - journals.plos.org
Extracellular trypanosomes can cause a wide range of diseases and pathological
complications in a broad range of mammalian hosts. One common feature of …

Effect of the treatment with Achyrocline satureioides (free and nanocapsules essential oil) and diminazene aceturate on hematological and biochemical parameters in …

GM Do Carmo, MD Baldissera, RA Vaucher… - Experimental …, 2015 - Elsevier
This study aimed to verify the effect of the treatment with A. satureioides essential oil (free
and nanoencapsulated forms) and diminazene aceturate on hematological and biochemical …

Effect of ivermectin on Trypanosoma brucei brucei in experimentally infected mice

UK Udensi, AF Fagbenro-Beyioku - Journal of vector borne …, 2012 - journals.lww.com
Background & objectives: Human and livestock African trypanosomiasis, otherwise known
as sleeping sickness, is a neglected tropical disease of public health importance in west and …

Chemotherapy of second stage human African trypanosomiasis: comparison between the parenteral diamidine DB829 and its oral prodrug DB868 in vervet monkeys

JK Thuita, KK Wolf, GA Murilla, AS Bridges… - PLoS neglected …, 2015 - journals.plos.org
Human African trypanosomiasis (HAT, sleeping sickness) ranks among the most neglected
tropical diseases based on limited availability of drugs that are safe and efficacious …

In vivo analysis of trypanocidal drug resistance in sahelian goats infected by Trypanosoma vivax strains collected in northern Togo

S Boma, SH Vitouley, MB Somda, Z Bengaly… - Veterinary …, 2022 - Elsevier
Trypanosoma (T.) vivax is one of the animal trypanosomes species causing calf mortality
and economic losses in Togo. Despite its importance as the most widely distributed …

Erythrina abyssinica prevents meningoencephalitis in chronic Trypanosoma brucei brucei mouse model

J Nasimolo, SG Kiama, PK Gathumbi… - Metabolic Brain …, 2014 - Springer
Human African trypanosomiasis is prevalent in Sub-sahara African countries that lie
between 14° North and 29° south of the equator. Sixty million people are at risk of infection …