[HTML][HTML] Non-animal approaches for photoallergenicity safety assessment: Needs and perspectives for the toxicology for the 21st century

RI de Ávila, M Aleksic, B Zhu, J Li, R Pendlington… - Regulatory Toxicology …, 2023 - Elsevier
Certain chemicals and/or their byproducts are photoactivated by UV/VIS and trigger a
dermal allergenic response, clinically recognized as photoallergic contact dermatitis …

New approach methodologies (NAMs) for the in vitro assessment of cleaning products for respiratory irritation: workshop report

LT Haber, MA Bradley, AN Buerger, H Behrsing… - Frontiers in …, 2024 - frontiersin.org
The use of in vitro new approach methodologies (NAMs) to assess respiratory irritation
depends on several factors, including the specifics of exposure methods and cell/tissue …

[HTML][HTML] Exposure considerations in human safety assessment: Report from an EPAA Partners' Forum

MTD Cronin, N Ball, S Beken, H Bender… - Regulatory Toxicology …, 2023 - Elsevier
Understanding and estimating the exposure to a substance is one of the fundamental
requirements for safe manufacture and use. Many approaches are taken to determine …

Identification and Risk Assessment of Antibiotics and Their Transformation Products in a Large-Scale River Using Suspect and Nontarget Screening and Machine …

Y Han, L Hu, CE Chen, S Liu, FZ Gao, JH Zhao… - ACS ES&T …, 2025 - ACS Publications
The occurrence of antibiotics in aquatic environments has been well-known, and more
research is needed about their transformation products (TPs) and associated environmental …

A botanical reference set illustrating a weight of evidence approach for skin sensitization risk assessment

Y Gao, CA Ryan, K Ellingson, N Krutz… - Food and Chemical …, 2024 - Elsevier
Recent years have seen an increase in the use of botanicals and natural substances (BNS)
in consumer products such as cosmetics and household care products. Most work …

Incorporating Singaporean habits and practices for cosmetics and personal care products into a global consumer aggregate exposure model

SA Juraimi, C Scrochi, J Lok, AM Api… - Regulatory Toxicology …, 2025 - Elsevier
Understanding consumer habits and practices of cosmetics and personal care products
(PCP) is essential to generate realistic product exposure data for the safety assessment of …

Roadmap for action for advancing aggregate exposure to chemicals in the EU

L Lamon, J Doyle, A Paini, R Moeller… - EFSA Supporting …, 2024 - Wiley Online Library
Abstract The European Food Safety Authority (EFSA) has a goal to efficiently conduct
aggregate exposure assessments (AEAs) for chemicals using both exposure models and …

[PDF][PDF] RIFM natural complex substance (NCS) fragrance ingredient safety assessment, petitgrain mandarin oil, CAS registry number 8014-17-3, RIFM ID: 250-E2. 12

AM Api, D Belsito, D Botelho… - Food and …, 2023 - fragrancematerialsafetyresource …
RIFM natural complex substance (NCS) fragrance ingredient safety assessment, petitgrain
mandarin oil, CAS registry number 8014-1 Page 1 Food and Chemical Toxicology 176 (2023) …

[PDF][PDF] RIFM natural complex substance (NCS) fragrance ingredient safety assessment, Mandarin oil terpenes, CAS registry number 68953-04-8, RIFM ID 250-G2. 30

AM Api, D Belsito, D Botelho… - Food and …, 2024 - fragrancematerialsafetyresource …
Summary: The existing information supports the use of this material as described in this
safety assessment. Mandarin oil terpenes was evaluated for genotoxicity, repeated dose …

[PDF][PDF] Cronin, MTD, Ball, N, Beken, S, Bender, H, Bercaru, O, Caneva, L, Corvaro, M, Currie, RA, Dawson, JL, Desert, P, Escher, SE, Franco, A, Irizar, A, Mehta, JM …

MTD Cronin - researchonline.ljmu.ac.uk
Exposure considerations in human safety assessment: Report from an EPAA Partners’ Forum
Page 1 Cronin, MTD, Ball, N, Beken, S, Bender, H, Bercaru, O, Caneva, L, Corvaro, M, Currie …