A Samii, JG Nutt, BR Ransom - The Lancet, 2004 - thelancet.com
Parkinson's disease is the most common serious movement disorder in the world, affecting about 1% of adults older than 60 years. The disease is attributed to selective loss of neurons …
AJ Fenoy, RK Simpson - Journal of neurosurgery, 2014 - thejns.org
Object Deep brain stimulation (DBS) surgery is increasingly prominent in the treatment of various disorders refractory to medication. Despite the procedure's efficacy, the community …
Short-term symptomatic treatment and dose-dependent side effects of pharmacological treatment for neurodegenerative diseases have forced the medical community to seek an …
MC Rodriguez-Oroz, JA Obeso, AE Lang, JL Houeto… - Brain, 2005 - academic.oup.com
Deep brain stimulation (DBS) is associated with significant improvement of motor complications in patients with severe Parkinson's disease after some 6–12 months of …
BD Greenberg, LA Gabriels, DA Malone, AR Rezai… - Molecular …, 2010 - nature.com
Psychiatric neurosurgery teams in the United States and Europe have studied deep brain stimulation (DBS) of the ventral anterior limb of the internal capsule and adjacent ventral …
L Zrinzo, T Foltynie, P Limousin, MI Hariz - Journal of neurosurgery, 2012 - thejns.org
Object Hemorrhagic complications carry by far the highest risk of devastating neurological outcome in functional neurosurgery. Literature published over the past 10 years suggests …
R Pahwa, SA Factor, KE Lyons, WG Ondo, G Gronseth… - Neurology, 2006 - AAN Enterprises
Objective: To make evidence-based treatment recommendations for the medical and surgical treatment of patients with Parkinson disease (PD) with levodopa-induced motor …
Parkinson's disease (PD) affects one in every 100 persons above the age of 65 years, making it the second most common neurodegenerative disease after Alzheimer's disease …
O Suchowersky, S Reich, J Perlmutter, T Zesiewicz… - Neurology, 2006 - AAN Enterprises
Objective: To define key issues in the diagnosis of Parkinson disease (PD), to define features influencing progression, and to make evidence-based recommendations. Two …