Metabolic syndrome and risk of cancer: a systematic review and meta-analysis

K Esposito, P Chiodini, A Colao, A Lenzi… - Diabetes …, 2012 - Am Diabetes Assoc
OBJECTIVE Available evidence supports the emerging hypothesis that metabolic syndrome
may be associated with the risk of some common cancers. We did a systematic review and …

APOA1: a protein with multiple therapeutic functions

BJ Cochran, KL Ong, B Manandhar, KA Rye - Current Atherosclerosis …, 2021 - Springer
Abstract Purpose of the Review Apolipoprotein (APO) A1, the main apolipoprotein of plasma
high-density lipoproteins (HDLs), has several well documented cardioprotective functions. A …

The role of the ATP-binding cassette A1 (ABCA1) in human disease

L Jacobo-Albavera, M Domínguez-Pérez… - International journal of …, 2021 - mdpi.com
Cholesterol homeostasis is essential in normal physiology of all cells. One of several
proteins involved in cholesterol homeostasis is the ATP-binding cassette transporter A1 …

The cardioprotective protein apolipoprotein A1 promotes potent anti-tumorigenic effects*♦

M Zamanian-Daryoush, D Lindner, TC Tallant… - Journal of biological …, 2013 - ASBMB
Here, we show that apolipoprotein A1 (apoA1), the major protein component of high density
lipoprotein (HDL), through both innate and adaptive immune processes, potently …

Apolipoproteins, lipids and risk of cancer

S Borgquist, T Butt, P Almgren… - … journal of cancer, 2016 - Wiley Online Library
The epidemiological evidence for an obesity‐cancer association is solid, whereas the
association between obesity‐associated lipoprotein levels and cancer is less evident. We …

HDL and LDL: potential new players in breast cancer development

L Cedó, ST Reddy, E Mato, F Blanco-Vaca… - Journal of clinical …, 2019 - mdpi.com
Breast cancer is the most prevalent cancer and primary cause of cancer-related mortality in
women. The identification of risk factors can improve prevention of cancer, and obesity and …

Shared risk factors for cardiovascular disease and cancer: implications for preventive health and clinical care in oncology patients

CB Johnson, MK Davis, A Law, J Sulpher - Canadian Journal of Cardiology, 2016 - Elsevier
The cardiovascular toxicity of cancer therapy has raised awareness of the importance of
heart disease in cancer care among oncologists and cardiologists, leading to the new …

The cholesterol transporter ABCG1 links cholesterol homeostasis and tumour immunity

D Sag, C Cekic, R Wu, J Linden, CC Hedrick - Nature communications, 2015 - nature.com
ATP-binding cassette transporter G1 (ABCG1) promotes cholesterol efflux from cells and
regulates intracellular cholesterol homeostasis. Here we demonstrate a role of ABCG1 as a …

Low high-density lipoprotein and increased risk of several cancers: 2 population-based cohort studies including 116,728 individuals

KM Pedersen, Y Çolak, SE Bojesen… - Journal of hematology & …, 2020 - Springer
Background Increasing evidence suggests that high-density lipoprotein (HDL) may play a
role in cancer development. We tested the hypothesis that low HDL levels are associated …

High-density lipoproteins and apolipoprotein A1

EPC van der Vorst - … and invertebrate respiratory proteins, lipoproteins and …, 2020 - Springer
High-density lipoprotein (HDL) and its main protein component apolipoprotein (apo) AI, play
an important role in cholesterol homeostasis. It has been demonstrated that HDLs comprise …