East African landscapes today are the result of the cumulative effects of climate and land-
use change over millennial timescales. In this review, we compile archaeological and …

Genetic information contains a record of the history of our species, and technological
advances have transformed our ability to access this record. Many studies have used …

Modern humans inhabit a variety of environments and are exposed to a plethora of selective
pressures, leading to multiple genetic adaptations to local environmental conditions. These …

Abstract The southern African indigenous Khoe-San populations harbor the most divergent
lineages of all living peoples. Exploring their genomes is key to understanding deep human …

Africa hosts the greatest human genetic diversity globally, but legacies of ancient population
interactions and dispersals across the continent remain understudied. Here, we report …

Abstract South Eastern Bantu-speaking (SEB) groups constitute more than 80% of the
population in South Africa. Despite clear linguistic and geographic diversity, the genetic …

In the last three decades, genetic studies have played an increasingly important role in
exploring human history. They have helped to conclusively establish that anatomically …

We used palaeoproteomics and peptide mass fingerprinting to obtain secure species
identifications of key specimens of early domesticated fauna from South Africa, dating to ca …

Identifying the causes of similarities and differences in genetic disease prevalence among
humans is central to understanding disease etiology. While present-day humans are not …

As the ancestral homeland of our species, Africa contains elevated levels of genetic diversity
and substantial population structure. Importantly, African genomes are heterogeneous: They …